Human Centromeres Produce Chromosome-Specific and Array-Specific Alpha Satellite Transcripts that Are Complexed with CENP-A and CENP-C

Human centromeres are defined by alpha satellite DNA arrays that are distinct and chromosome specific. Most human chromosomes contain multiple alpha satellite arrays that are competent for centromere assembly. Here, we show that human centromeres are defined by chromosome-specific RNAs linked to und...

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Veröffentlicht in:Developmental cell 2017-08, Vol.42 (3), p.226-240.e6
Hauptverfasser: McNulty, Shannon M., Sullivan, Lori L., Sullivan, Beth A.
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Sprache:eng
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