Circadian and Feeding Rhythms Orchestrate the Diurnal Liver Acetylome

Lysine acetylation is involved in various biological processes and is considered a key reversible post-translational modification in the regulation of gene expression, enzyme activity, and subcellular localization. This post-translational modification is therefore highly relevant in the context of c...

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Veröffentlicht in:	Cell reports (Cambridge) 2017-08, Vol.20 (7), p.1729-1743
Hauptverfasser:	Mauvoisin, Daniel, Atger, Florian, Dayon, Loïc, Núñez Galindo, Antonio, Wang, Jingkui, Martin, Eva, Da Silva, Laetitia, Montoliu, Ivan, Collino, Sebastiano, Martin, Francois-Pierre, Ratajczak, Joanna, Cantó, Carles, Kussmann, Martin, Naef, Felix, Gachon, Frédéric
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Animals ARNTL Transcription Factors - deficiency ARNTL Transcription Factors - genetics circadian clock Circadian Clocks - physiology Circadian Rhythm - physiology Cryptochromes - deficiency Cryptochromes - genetics Eating - physiology Liver - enzymology liver metabolism Lysine Metabolic Networks and Pathways - physiology Mice Mice, Inbred C57BL Mice, Knockout Mitochondrial Proteins - genetics Mitochondrial Proteins - metabolism NAD NAD - metabolism Photoperiod Protein Processing, Post-Translational Proteome - genetics Proteome - metabolism Resource SILAC proteomics SIRT3 Sirtuin 3 - genetics Sirtuin 3 - metabolism
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