Polycomb-mediated chromatin loops revealed by a subkilobase-resolution chromatin interaction map

The locations of chromatin loops in Drosophila were determined by Hi-C (chemical cross-linking, restriction digestion, ligation, and high-throughput DNA sequencing). Whereas most loop boundaries or “anchors” are associated with CTCF protein in mammals, loop anchors in Drosophila were found most ofte...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2017-08, Vol.114 (33), p.8764-8769
Hauptverfasser:	Eagen, Kyle P., Aiden, Erez Lieberman, Kornberg, Roger D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Sciences Chromatin Chromosomes Crosslinking CTCF protein Deoxyribonucleic acid DNA DNA sequencing Drosophila Loops Polycomb group proteins Promoters
Online-Zugang:	Volltext
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