Micrornas in prostate cancer: an overview
Prostate cancer is the second highest cause of cancer mortality after lung tumours. In USA it affects about 2.8 million men and the incidence increases with age in many countries. Therefore, early diagnosis is a very important step for patient clinical evaluation and for a selective and efficient th...
Gespeichert in:
| Veröffentlicht in: | Oncotarget 2017-07, Vol.8 (30), p.50240-50251 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 50251 |
|---|---|
| container_issue | 30 |
| container_start_page | 50240 |
| container_title | Oncotarget |
| container_volume | 8 |
| creator | Vanacore, Daniela Boccellino, Mariarosaria Rossetti, Sabrina Cavaliere, Carla D'Aniello, Carmine Di Franco, Rossella Romano, Francesco Jacopo Montanari, Micaela La Mantia, Elvira Piscitelli, Raffaele Nocerino, Flavia Cappuccio, Francesca Grimaldi, Giovanni Izzo, Alessandro Castaldo, Luigi Pepe, Maria Filomena Malzone, Maria Gabriella Iovane, Gelsomina Ametrano, Gianluca Stiuso, Paola Quagliuolo, Lucio Barberio, Daniela Perdonà, Sisto Muto, Paolo Montella, Maurizio Maiolino, Piera Veneziani, Bianca Maria Botti, Gerardo Caraglia, Michele Facchini, Gaetano |
| description | Prostate cancer is the second highest cause of cancer mortality after lung tumours. In USA it affects about 2.8 million men and the incidence increases with age in many countries. Therefore, early diagnosis is a very important step for patient clinical evaluation and for a selective and efficient therapy. The study of miRNAs' functions and molecular mechanisms has brought new knowledge in biological processes of cancer. In prostate cancer there is a deregulation of several miRNAs that may function as tumour suppressors or oncogenes. The aim of this review is to analyze the progress made to our understanding of the role of miRNA dysregulation in prostate cancer tumourigenesis. |
| doi_str_mv | 10.18632/oncotarget.16933 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5564846</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1892726085</sourcerecordid><originalsourceid>FETCH-LOGICAL-c356t-e3f7101700cb2c58b1339fed428a77818783aeef071520592296f55e7d4263253</originalsourceid><addsrcrecordid>eNpVkE1PwzAMhiMEYtPYD-CCeoRDRz6aJuGAhCa-pCEucI6yzB1FXTKSrIh_T9nGGL7Yku33tR-ETgkeEVkyeumd9cmEOaQRKRVjB6hPVKFyyjk73Kt7aBjjO-6CF0JSdYx6VBYFJ4z30cVTbYMPzsSsdtky-JhMgswaZyFcZcZlvoXQ1vB5go4q00QYbvMAvd7dvowf8snz_eP4ZpJbxsuUA6sEwURgbKfUcjkljKkKZgWVRghJpJDMAFRYEE4xV5SqsuIcRDfRfcXZAF1vdJer6QJmFlwKptHLUC9M-NLe1Pp_x9Vveu5bzXlZyKLsBM63AsF_rCAmvaijhaYxDvwqaiIVFbTE8seLbEY7BjEGqHY2BOs1Zf1HWa8pdztn-_ftNn6Zsm8BMHoS</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1892726085</pqid></control><display><type>article</type><title>Micrornas in prostate cancer: an overview</title><source>MEDLINE</source><source>PubMed Central</source><source>Free E- Journals</source><source>EZB Electronic Journals Library</source><source>PubMed Central Open Access</source><creator>Vanacore, Daniela ; Boccellino, Mariarosaria ; Rossetti, Sabrina ; Cavaliere, Carla ; D'Aniello, Carmine ; Di Franco, Rossella ; Romano, Francesco Jacopo ; Montanari, Micaela ; La Mantia, Elvira ; Piscitelli, Raffaele ; Nocerino, Flavia ; Cappuccio, Francesca ; Grimaldi, Giovanni ; Izzo, Alessandro ; Castaldo, Luigi ; Pepe, Maria Filomena ; Malzone, Maria Gabriella ; Iovane, Gelsomina ; Ametrano, Gianluca ; Stiuso, Paola ; Quagliuolo, Lucio ; Barberio, Daniela ; Perdonà, Sisto ; Muto, Paolo ; Montella, Maurizio ; Maiolino, Piera ; Veneziani, Bianca Maria ; Botti, Gerardo ; Caraglia, Michele ; Facchini, Gaetano</creator><creatorcontrib>Vanacore, Daniela ; Boccellino, Mariarosaria ; Rossetti, Sabrina ; Cavaliere, Carla ; D'Aniello, Carmine ; Di Franco, Rossella ; Romano, Francesco Jacopo ; Montanari, Micaela ; La Mantia, Elvira ; Piscitelli, Raffaele ; Nocerino, Flavia ; Cappuccio, Francesca ; Grimaldi, Giovanni ; Izzo, Alessandro ; Castaldo, Luigi ; Pepe, Maria Filomena ; Malzone, Maria Gabriella ; Iovane, Gelsomina ; Ametrano, Gianluca ; Stiuso, Paola ; Quagliuolo, Lucio ; Barberio, Daniela ; Perdonà, Sisto ; Muto, Paolo ; Montella, Maurizio ; Maiolino, Piera ; Veneziani, Bianca Maria ; Botti, Gerardo ; Caraglia, Michele ; Facchini, Gaetano</creatorcontrib><description>Prostate cancer is the second highest cause of cancer mortality after lung tumours. In USA it affects about 2.8 million men and the incidence increases with age in many countries. Therefore, early diagnosis is a very important step for patient clinical evaluation and for a selective and efficient therapy. The study of miRNAs' functions and molecular mechanisms has brought new knowledge in biological processes of cancer. In prostate cancer there is a deregulation of several miRNAs that may function as tumour suppressors or oncogenes. The aim of this review is to analyze the progress made to our understanding of the role of miRNA dysregulation in prostate cancer tumourigenesis.</description><identifier>ISSN: 1949-2553</identifier><identifier>EISSN: 1949-2553</identifier><identifier>DOI: 10.18632/oncotarget.16933</identifier><identifier>PMID: 28445135</identifier><language>eng</language><publisher>United States: Impact Journals LLC</publisher><subject>Biomarkers, Tumor - genetics ; Genes, Tumor Suppressor - physiology ; Humans ; Male ; MicroRNAs - genetics ; Prostatic Neoplasms - genetics ; Prostatic Neoplasms - pathology ; Review</subject><ispartof>Oncotarget, 2017-07, Vol.8 (30), p.50240-50251</ispartof><rights>Copyright: © 2017 Vanacore et al. 2017</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c356t-e3f7101700cb2c58b1339fed428a77818783aeef071520592296f55e7d4263253</citedby><cites>FETCH-LOGICAL-c356t-e3f7101700cb2c58b1339fed428a77818783aeef071520592296f55e7d4263253</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564846/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564846/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28445135$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vanacore, Daniela</creatorcontrib><creatorcontrib>Boccellino, Mariarosaria</creatorcontrib><creatorcontrib>Rossetti, Sabrina</creatorcontrib><creatorcontrib>Cavaliere, Carla</creatorcontrib><creatorcontrib>D'Aniello, Carmine</creatorcontrib><creatorcontrib>Di Franco, Rossella</creatorcontrib><creatorcontrib>Romano, Francesco Jacopo</creatorcontrib><creatorcontrib>Montanari, Micaela</creatorcontrib><creatorcontrib>La Mantia, Elvira</creatorcontrib><creatorcontrib>Piscitelli, Raffaele</creatorcontrib><creatorcontrib>Nocerino, Flavia</creatorcontrib><creatorcontrib>Cappuccio, Francesca</creatorcontrib><creatorcontrib>Grimaldi, Giovanni</creatorcontrib><creatorcontrib>Izzo, Alessandro</creatorcontrib><creatorcontrib>Castaldo, Luigi</creatorcontrib><creatorcontrib>Pepe, Maria Filomena</creatorcontrib><creatorcontrib>Malzone, Maria Gabriella</creatorcontrib><creatorcontrib>Iovane, Gelsomina</creatorcontrib><creatorcontrib>Ametrano, Gianluca</creatorcontrib><creatorcontrib>Stiuso, Paola</creatorcontrib><creatorcontrib>Quagliuolo, Lucio</creatorcontrib><creatorcontrib>Barberio, Daniela</creatorcontrib><creatorcontrib>Perdonà, Sisto</creatorcontrib><creatorcontrib>Muto, Paolo</creatorcontrib><creatorcontrib>Montella, Maurizio</creatorcontrib><creatorcontrib>Maiolino, Piera</creatorcontrib><creatorcontrib>Veneziani, Bianca Maria</creatorcontrib><creatorcontrib>Botti, Gerardo</creatorcontrib><creatorcontrib>Caraglia, Michele</creatorcontrib><creatorcontrib>Facchini, Gaetano</creatorcontrib><title>Micrornas in prostate cancer: an overview</title><title>Oncotarget</title><addtitle>Oncotarget</addtitle><description>Prostate cancer is the second highest cause of cancer mortality after lung tumours. In USA it affects about 2.8 million men and the incidence increases with age in many countries. Therefore, early diagnosis is a very important step for patient clinical evaluation and for a selective and efficient therapy. The study of miRNAs' functions and molecular mechanisms has brought new knowledge in biological processes of cancer. In prostate cancer there is a deregulation of several miRNAs that may function as tumour suppressors or oncogenes. The aim of this review is to analyze the progress made to our understanding of the role of miRNA dysregulation in prostate cancer tumourigenesis.</description><subject>Biomarkers, Tumor - genetics</subject><subject>Genes, Tumor Suppressor - physiology</subject><subject>Humans</subject><subject>Male</subject><subject>MicroRNAs - genetics</subject><subject>Prostatic Neoplasms - genetics</subject><subject>Prostatic Neoplasms - pathology</subject><subject>Review</subject><issn>1949-2553</issn><issn>1949-2553</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkE1PwzAMhiMEYtPYD-CCeoRDRz6aJuGAhCa-pCEucI6yzB1FXTKSrIh_T9nGGL7Yku33tR-ETgkeEVkyeumd9cmEOaQRKRVjB6hPVKFyyjk73Kt7aBjjO-6CF0JSdYx6VBYFJ4z30cVTbYMPzsSsdtky-JhMgswaZyFcZcZlvoXQ1vB5go4q00QYbvMAvd7dvowf8snz_eP4ZpJbxsuUA6sEwURgbKfUcjkljKkKZgWVRghJpJDMAFRYEE4xV5SqsuIcRDfRfcXZAF1vdJer6QJmFlwKptHLUC9M-NLe1Pp_x9Vveu5bzXlZyKLsBM63AsF_rCAmvaijhaYxDvwqaiIVFbTE8seLbEY7BjEGqHY2BOs1Zf1HWa8pdztn-_ftNn6Zsm8BMHoS</recordid><startdate>20170725</startdate><enddate>20170725</enddate><creator>Vanacore, Daniela</creator><creator>Boccellino, Mariarosaria</creator><creator>Rossetti, Sabrina</creator><creator>Cavaliere, Carla</creator><creator>D'Aniello, Carmine</creator><creator>Di Franco, Rossella</creator><creator>Romano, Francesco Jacopo</creator><creator>Montanari, Micaela</creator><creator>La Mantia, Elvira</creator><creator>Piscitelli, Raffaele</creator><creator>Nocerino, Flavia</creator><creator>Cappuccio, Francesca</creator><creator>Grimaldi, Giovanni</creator><creator>Izzo, Alessandro</creator><creator>Castaldo, Luigi</creator><creator>Pepe, Maria Filomena</creator><creator>Malzone, Maria Gabriella</creator><creator>Iovane, Gelsomina</creator><creator>Ametrano, Gianluca</creator><creator>Stiuso, Paola</creator><creator>Quagliuolo, Lucio</creator><creator>Barberio, Daniela</creator><creator>Perdonà, Sisto</creator><creator>Muto, Paolo</creator><creator>Montella, Maurizio</creator><creator>Maiolino, Piera</creator><creator>Veneziani, Bianca Maria</creator><creator>Botti, Gerardo</creator><creator>Caraglia, Michele</creator><creator>Facchini, Gaetano</creator><general>Impact Journals LLC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20170725</creationdate><title>Micrornas in prostate cancer: an overview</title><author>Vanacore, Daniela ; Boccellino, Mariarosaria ; Rossetti, Sabrina ; Cavaliere, Carla ; D'Aniello, Carmine ; Di Franco, Rossella ; Romano, Francesco Jacopo ; Montanari, Micaela ; La Mantia, Elvira ; Piscitelli, Raffaele ; Nocerino, Flavia ; Cappuccio, Francesca ; Grimaldi, Giovanni ; Izzo, Alessandro ; Castaldo, Luigi ; Pepe, Maria Filomena ; Malzone, Maria Gabriella ; Iovane, Gelsomina ; Ametrano, Gianluca ; Stiuso, Paola ; Quagliuolo, Lucio ; Barberio, Daniela ; Perdonà, Sisto ; Muto, Paolo ; Montella, Maurizio ; Maiolino, Piera ; Veneziani, Bianca Maria ; Botti, Gerardo ; Caraglia, Michele ; Facchini, Gaetano</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c356t-e3f7101700cb2c58b1339fed428a77818783aeef071520592296f55e7d4263253</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Biomarkers, Tumor - genetics</topic><topic>Genes, Tumor Suppressor - physiology</topic><topic>Humans</topic><topic>Male</topic><topic>MicroRNAs - genetics</topic><topic>Prostatic Neoplasms - genetics</topic><topic>Prostatic Neoplasms - pathology</topic><topic>Review</topic><toplevel>online_resources</toplevel><creatorcontrib>Vanacore, Daniela</creatorcontrib><creatorcontrib>Boccellino, Mariarosaria</creatorcontrib><creatorcontrib>Rossetti, Sabrina</creatorcontrib><creatorcontrib>Cavaliere, Carla</creatorcontrib><creatorcontrib>D'Aniello, Carmine</creatorcontrib><creatorcontrib>Di Franco, Rossella</creatorcontrib><creatorcontrib>Romano, Francesco Jacopo</creatorcontrib><creatorcontrib>Montanari, Micaela</creatorcontrib><creatorcontrib>La Mantia, Elvira</creatorcontrib><creatorcontrib>Piscitelli, Raffaele</creatorcontrib><creatorcontrib>Nocerino, Flavia</creatorcontrib><creatorcontrib>Cappuccio, Francesca</creatorcontrib><creatorcontrib>Grimaldi, Giovanni</creatorcontrib><creatorcontrib>Izzo, Alessandro</creatorcontrib><creatorcontrib>Castaldo, Luigi</creatorcontrib><creatorcontrib>Pepe, Maria Filomena</creatorcontrib><creatorcontrib>Malzone, Maria Gabriella</creatorcontrib><creatorcontrib>Iovane, Gelsomina</creatorcontrib><creatorcontrib>Ametrano, Gianluca</creatorcontrib><creatorcontrib>Stiuso, Paola</creatorcontrib><creatorcontrib>Quagliuolo, Lucio</creatorcontrib><creatorcontrib>Barberio, Daniela</creatorcontrib><creatorcontrib>Perdonà, Sisto</creatorcontrib><creatorcontrib>Muto, Paolo</creatorcontrib><creatorcontrib>Montella, Maurizio</creatorcontrib><creatorcontrib>Maiolino, Piera</creatorcontrib><creatorcontrib>Veneziani, Bianca Maria</creatorcontrib><creatorcontrib>Botti, Gerardo</creatorcontrib><creatorcontrib>Caraglia, Michele</creatorcontrib><creatorcontrib>Facchini, Gaetano</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Oncotarget</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vanacore, Daniela</au><au>Boccellino, Mariarosaria</au><au>Rossetti, Sabrina</au><au>Cavaliere, Carla</au><au>D'Aniello, Carmine</au><au>Di Franco, Rossella</au><au>Romano, Francesco Jacopo</au><au>Montanari, Micaela</au><au>La Mantia, Elvira</au><au>Piscitelli, Raffaele</au><au>Nocerino, Flavia</au><au>Cappuccio, Francesca</au><au>Grimaldi, Giovanni</au><au>Izzo, Alessandro</au><au>Castaldo, Luigi</au><au>Pepe, Maria Filomena</au><au>Malzone, Maria Gabriella</au><au>Iovane, Gelsomina</au><au>Ametrano, Gianluca</au><au>Stiuso, Paola</au><au>Quagliuolo, Lucio</au><au>Barberio, Daniela</au><au>Perdonà, Sisto</au><au>Muto, Paolo</au><au>Montella, Maurizio</au><au>Maiolino, Piera</au><au>Veneziani, Bianca Maria</au><au>Botti, Gerardo</au><au>Caraglia, Michele</au><au>Facchini, Gaetano</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Micrornas in prostate cancer: an overview</atitle><jtitle>Oncotarget</jtitle><addtitle>Oncotarget</addtitle><date>2017-07-25</date><risdate>2017</risdate><volume>8</volume><issue>30</issue><spage>50240</spage><epage>50251</epage><pages>50240-50251</pages><issn>1949-2553</issn><eissn>1949-2553</eissn><abstract>Prostate cancer is the second highest cause of cancer mortality after lung tumours. In USA it affects about 2.8 million men and the incidence increases with age in many countries. Therefore, early diagnosis is a very important step for patient clinical evaluation and for a selective and efficient therapy. The study of miRNAs' functions and molecular mechanisms has brought new knowledge in biological processes of cancer. In prostate cancer there is a deregulation of several miRNAs that may function as tumour suppressors or oncogenes. The aim of this review is to analyze the progress made to our understanding of the role of miRNA dysregulation in prostate cancer tumourigenesis.</abstract><cop>United States</cop><pub>Impact Journals LLC</pub><pmid>28445135</pmid><doi>10.18632/oncotarget.16933</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1949-2553 |
| ispartof | Oncotarget, 2017-07, Vol.8 (30), p.50240-50251 |
| issn | 1949-2553 1949-2553 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5564846 |
| source | MEDLINE; PubMed Central; Free E- Journals; EZB Electronic Journals Library; PubMed Central Open Access |
| subjects | Biomarkers, Tumor - genetics Genes, Tumor Suppressor - physiology Humans Male MicroRNAs - genetics Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology Review |
| title | Micrornas in prostate cancer: an overview |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-01T12%3A00%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Micrornas%20in%20prostate%20cancer:%20an%20overview&rft.jtitle=Oncotarget&rft.au=Vanacore,%20Daniela&rft.date=2017-07-25&rft.volume=8&rft.issue=30&rft.spage=50240&rft.epage=50251&rft.pages=50240-50251&rft.issn=1949-2553&rft.eissn=1949-2553&rft_id=info:doi/10.18632/oncotarget.16933&rft_dat=%3Cproquest_pubme%3E1892726085%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1892726085&rft_id=info:pmid/28445135&rfr_iscdi=true |