Proteins are potent biomarkers to detect colon cancer progression
Colon cancer is the most common type of cancer and major cause of death worldwide. The detection of colon cancer is difficult in early stages. However, the secretory proteins have been used as ideal biomarker for the detection of colon cancer progress in cancer patients. Serum/tissue protein express...
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| Veröffentlicht in: | Saudi journal of biological sciences 2017-09, Vol.24 (6), p.1212-1221 |
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| container_title | Saudi journal of biological sciences |
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| creator | Kuppusamy, Palaniselvam Govindan, Natanamurugaraj Yusoff, Mashitah M. Ichwan, Solachuddin J.A. |
| description | Colon cancer is the most common type of cancer and major cause of death worldwide. The detection of colon cancer is difficult in early stages. However, the secretory proteins have been used as ideal biomarker for the detection of colon cancer progress in cancer patients. Serum/tissue protein expression could help general practitioners to identify colon cancer at earlier stages. By this way, we use the biomarkers to evaluate the anticancer drugs and their response to therapy in cancer models. Recently, the biomarker discovery is important in cancer biology and disease management. Also, many measurable specific molecular components have been studied in colon cancer therapeutics. The biomolecules are mainly DNA, RNA, metabolites, enzymes, mRNA, aptamers and proteins. Thus, in this review we demonstrate the important protein biomarker in colon cancer development and molecular identification of protein biomarker discovery. |
| doi_str_mv | 10.1016/j.sjbs.2014.09.017 |
| format | Article |
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The detection of colon cancer is difficult in early stages. However, the secretory proteins have been used as ideal biomarker for the detection of colon cancer progress in cancer patients. Serum/tissue protein expression could help general practitioners to identify colon cancer at earlier stages. By this way, we use the biomarkers to evaluate the anticancer drugs and their response to therapy in cancer models. Recently, the biomarker discovery is important in cancer biology and disease management. Also, many measurable specific molecular components have been studied in colon cancer therapeutics. The biomolecules are mainly DNA, RNA, metabolites, enzymes, mRNA, aptamers and proteins. 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| source | Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | antineoplastic agents Biomarkers blood serum carcinogenesis Colon cancer colorectal neoplasms death disease control disease course DNA enzymes general practitioners messenger RNA metabolites oligonucleotides Original patients protein synthesis proteins Proteomic techniques Secretory proteins therapeutics |
| title | Proteins are potent biomarkers to detect colon cancer progression |
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