Evaluation of Safety in Exceeding Maximum Adult Doses of Commonly Used Second-Generation Antiepileptic Drugs in Pediatric Patients

Pediatric patients often require larger doses of antiepileptic drug (AED) than adults in order to attain therapeutic serum concentrations and/or achieve seizure control. Safety and efficacy data are often extrapolated from adult literature; hence, optimal dosage may only be determined anecdotally or...

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Veröffentlicht in:	The journal of pediatric pharmacology and therapeutics 2017-07, Vol.22 (4), p.256-260
Hauptverfasser:	Messinger, Mindl M, Misra, Sunita N, Clark, Gary D, DiCarlo, Shannon M
Format:	Artikel
Sprache:	eng
Schlagworte:	Clinical Investigations
Online-Zugang:	Volltext
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