Otoprotective effects of mouse nerve growth factor in DBA/2J mice with early‐onset progressive hearing loss

As it displays progressive hair‐cell loss and degeneration of spiral ganglion neurons (SGNs) characterized by early‐onset progressive hearing loss (ePHL), DBA/2J is an inbred mouse strain widely used in hearing research. Mouse nerve growth factor (mNGF), as a common exogenous nerve growth factor (NG...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neuroscience research 2017-10, Vol.95 (10), p.1937-1950
Hauptverfasser:	Wang, Qingzhu, Zhao, Hongchun, Zheng, Tihua, Wang, Wenjun, Zhang, Xiaolin, Wang, Andi, Li, Bo, Wang, Yanfei, Zheng, Qingyin
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Apoptosis BAK protein BAX protein Brain stem Caspase Degeneration Growth factors Hair hair cells Hearing loss Hearing protection Immunohistochemistry Inbreeding Intervention Mice Mitochondria mitochondrial pathway mouse model mouse nerve growth factor Nerve growth factor Polymerase chain reaction progressive hearing loss Proteins Rodents Spiral ganglion spiral ganglion neurons Therapeutic applications Thresholds
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!