Accumulation of methylglyoxal increases the advanced glycation end-product levels in DRG and contributes to lumbar disk herniation-induced persistent pain

Lumbar disk herniation (LDH) with discogenic low back pain and sciatica is a common and complicated musculoskeletal disorder. The underlying mechanisms are poorly understood, and there are no effective therapies for LDH-induced pain. In the present study, we found that the patients who suffered from...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of neurophysiology 2017-08, Vol.118 (2), p.1321-1328
Hauptverfasser:	Liu, Cui-Cui, Zhang, Xin-Sheng, Ruan, Yu-Ting, Huang, Zhu-Xi, Zhang, Su-Bo, Liu, Meng, Luo, Hai-Jie, Wu, Shao-Ling, Ma, Chao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ganglia, Spinal - metabolism Glycation End Products, Advanced - metabolism Humans Intervertebral Disc Displacement - complications Intervertebral Disc Displacement - metabolism Low Back Pain - etiology Low Back Pain - metabolism Lumbosacral Region - pathology Male Pyruvaldehyde - metabolism Rats Rats, Sprague-Dawley
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!