Functional Genomic Analysis of the Rates of Protein Evolution

The evolutionary rates of proteins vary over several orders of magnitude. Recent work suggests that analysis of large data sets of evolutionary rates in conjunction with the results from high-throughput functional genomic experiments can identify the factors that cause proteins to evolve at such dra...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2005-04, Vol.102 (15), p.5483-5488
Hauptverfasser:	Wall, Dennis P., Hirsh, Aaron E., Fraser, Hunter B., Kumm, Jochen, Giaever, Guri, Eisen, Michael B., Feldman, Marcus W., Kirschner, Marc W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biological evolution Biological Sciences Correlation coefficients Correlations Datasets Estimate reliability Evolution Evolution, Molecular Fungal Proteins - chemistry Fungal Proteins - genetics Genes, Fungal - genetics Genome, Fungal Genomes Genomics Messenger RNA Models, Statistical Proteins Saccharomyces Saccharomyces - classification Saccharomyces - genetics Time Factors Yeasts
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