Efficacy of tolvaptan for the patients with advanced hepatocellular carcinoma

AIM To investigate the factors influenced the efficacy of tolvaptan(TLV) in liver cirrhosis.METHODS We retrospectively enrolled 61 consecutive patients with refractory hepatic ascites. All of them had been treated with furosemide and spironolactone before admission, and treated with TLV for 7 d in o...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2017-08, Vol.23 (29), p.5379-5385
Hauptverfasser:	Miyazaki, Masayuki, Yada, Masayoshi, Tanaka, Kosuke, Senjyu, Takeshi, Goya, Takeshi, Motomura, Kenta, Kohjima, Motoyuki, Kato, Masaki, Masumoto, Akihide, Kotoh, Kazuhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Antidiuretic Hormone Receptor Antagonists - pharmacology Antidiuretic Hormone Receptor Antagonists - therapeutic use Ascites - drug therapy Ascites - etiology Benzazepines - pharmacology Benzazepines - therapeutic use Body Weight - drug effects Carcinoma, Hepatocellular - complications Carcinoma, Hepatocellular - drug therapy Carcinoma, Hepatocellular - pathology Disease Progression Diuretics - pharmacology Diuretics - therapeutic use Dose-Response Relationship, Drug Drug Interactions Drug Resistance Drug Therapy, Combination - methods Female Furosemide - therapeutic use Humans Liver Liver Failure - drug therapy Liver Failure - etiology Liver Failure - pathology Liver Neoplasms - drug therapy Liver Neoplasms - pathology Male Middle Aged Neoplasm Staging Retrospective Studies Retrospective Study Spironolactone - therapeutic use Treatment Outcome
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