Lymphocyte Subsets in HIV-Exposed Uninfected Infants and HIV-Unexposed Uninfected Infants

HIV and its proteins, which are known to inhibit progenitor cell function and cause progenitor cell apoptosis, cross the placental barrier, potentially leading to infant immunologic deficiency.1 Studies have demonstrated reduced numbers of CD4 T cells, increased numbers of CD8 T cells and CD19 B cel...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2017-08, Vol.140 (2), p.605-608.e3
Hauptverfasser:	Huo, Yanling, MS, Patel, Kunjal, DSc, MPH, Scott, Gwendolyn B., MD, Van Dyke, Russell B., MD, Siberry, George K., MD, Burchett, Sandra K., MD, MS, Shearer, William T., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome AIDS Alcoholic beverages Allergy and Immunology Antiretroviral agents Apoptosis CD19 antigen CD4 antigen CD8 antigen Cell activation Clinical trials Disease control HIV Human immunodeficiency virus Infants Lymphocytes Lymphocytes B Lymphocytes T Placenta Pregnancy Progenitor cells Prophylaxis Proteins T cell receptors Zidovudine
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