The calcium-activated potassium channel KCa3.1 plays a central role in the chemotactic response of mammalian neutrophils

Aim Neutrophils are the first cells to arrive at sites of injury. Nevertheless, many inflammatory diseases are characterized by an uncontrolled infiltration and action of these cells. Cell migration depends on volume changes that are governed by ion channel activity, but potassium channels in neutro...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Acta Physiologica 2016-01, Vol.216 (1), p.132-145
Hauptverfasser:	Henríquez, C., Riquelme, T. T., Vera, D., Julio-Kalajzić, F., Ehrenfeld, P., Melvin, J. E., Figueroa, C. D., Sarmiento, J., Flores, C. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - metabolism Chemotaxis Humans Inflammation Intermediate-Conductance Calcium-Activated Potassium Channels - metabolism KCa3.1 Membrane Potentials - physiology neutrophil Neutrophils - cytology Neutrophils - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!