Metabolic Regulation of T Cell Longevity and Function in Tumor Immunotherapy

Cancer immunotherapy is an increasingly successful strategy for the treatment of patients who have advanced or conventional therapy-resistant cancers. T cells are key mediators of tumor destruction and their specificity for tumor-expressed antigens is of paramount importance, but other T cell-intrin...

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Veröffentlicht in:Cell metabolism 2017-07, Vol.26 (1), p.94-109
Hauptverfasser: Kishton, Rigel J., Sukumar, Madhusudhanan, Restifo, Nicholas P.
Format: Artikel
Sprache:eng
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