Munc18c Regulates Insulin-stimulated GLUT4 Translocation to the Transverse Tubules in Skeletal Muscle

To examine the intracellular trafficking and translocation of GLUT4 in skeletal muscle, we have generated transgenic mouse lines that specifically express a GLUT4-EGFP (enhanced green fluorescent protein) fusion protein under the control of the human skeletal muscle actin promoter. These transgenic...

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Veröffentlicht in:	The Journal of biological chemistry 2001-02, Vol.276 (6), p.4063-4069
Hauptverfasser:	Khan, Ahmir H., Thurmond, Debbie C., Yang, Chunmei, Ceresa, Brian P., Sigmund, Curt D., Pessin, Jeffrey E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Glucose Transporter Type 4 Green Fluorescent Proteins Insulin - pharmacology Luminescent Proteins - genetics Mice Mice, Transgenic Monosaccharide Transport Proteins - genetics Monosaccharide Transport Proteins - metabolism Munc18 Proteins Muscle Proteins Muscle, Skeletal - drug effects Muscle, Skeletal - metabolism Nerve Tissue Proteins Protein Transport Proteins - physiology Vesicular Transport Proteins
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