Autophagy-Dependent Beneficial Effects of Exercise

Autophagy-Dependent Beneficial Effects of Exercise

Exercise has long been recognized as a powerful physiological stimulus for a wide variety of metabolic adaptations with implications for health and performance. The metabolic effects of exercise occur during and after each exercise bout and manifest as cumulative adaptive responses to successive exe...

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Veröffentlicht in:Cold Spring Harbor perspectives in medicine 2017-08, Vol.7 (8), p.a029777
Hauptverfasser: Halling, Jens Frey, Pilegaard, Henriette
Format: Artikel
Sprache:eng
Schlagworte:
Adaptation, Physiological - physiology
Animals
Autophagy - physiology
Exercise - physiology
Gene Expression Regulation
Humans
Muscle, Skeletal - metabolism
Muscle, Skeletal - physiology
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Pilegaard, Henriette
description Exercise has long been recognized as a powerful physiological stimulus for a wide variety of metabolic adaptations with implications for health and performance. The metabolic effects of exercise occur during and after each exercise bout and manifest as cumulative adaptive responses to successive exercise bouts. Studies on the beneficial effects of exercise have traditionally focused on the biosynthesis of metabolic proteins and organelles. However, the recycling of cellular components by autophagy has recently emerged as an important process involved in the adaptive responses to exercise. This review covers the regulation of autophagy by exercise, with emphasis on the potential autophagy-dependent beneficial effects of exercise.
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subjects Adaptation, Physiological - physiology
Animals
Autophagy - physiology
Exercise - physiology
Gene Expression Regulation
Humans
Muscle, Skeletal - metabolism
Muscle, Skeletal - physiology
title Autophagy-Dependent Beneficial Effects of Exercise
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