A new long noncoding RNA (lncRNA) is induced in cutaneous squamous cell carcinoma and down-regulates several anticancer and cell differentiation genes in mouse

Keratinocyte-derived cutaneous squamous cell carcinoma (cSCC) is the most common metastatic skin cancer. Although some of the early events involved in this pathology have been identified, the subsequent steps leading to tumor development are poorly defined. We demonstrate here that the development o...

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Veröffentlicht in:	The Journal of biological chemistry 2017-07, Vol.292 (30), p.12483-12495
Hauptverfasser:	Ponzio, Gilles, Rezzonico, Roger, Bourget, Isabelle, Allan, Richard, Nottet, Nicolas, Popa, Alexandra, Magnone, Virginie, Rios, Géraldine, Mari, Bernard, Barbry, Pascal
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals cancer biology Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - pathology Cell Differentiation - genetics Cellular Biology Down-Regulation - genetics Female Gene Regulation Life Sciences long noncoding RNA (long ncRNA, lncRNA) Mice Mice, Inbred Strains microarray RNA RNA, Long Noncoding - genetics skin Skin Neoplasms - genetics Skin Neoplasms - pathology Tumor Cells, Cultured
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