The hormone response element of the mouse mammary tumour virus DNA mediates the progestin and androgen induction of transcription in the proviral long terminal repeat region

Mouse mammary tumour virus (MMTV) gene expression has been shown to be regulated by glucocorticoids. A hormone response element (HRE) located between ‐202 and ‐59 upstream of the start of transcription in the long terminal repeat (LTR) region of the proviral DNA is required for this induction. We ha...

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Veröffentlicht in:	The EMBO journal 1987-02, Vol.6 (2), p.363-368
Hauptverfasser:	Cato, A.C., Henderson, D., Ponta, H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetyltransferases - genetics Androgens - pharmacology Animals Biological and medical sciences Breast Neoplasms Cell Line Chloramphenicol O-Acetyltransferase DNA, Viral - drug effects DNA, Viral - genetics Estradiol - pharmacology Female Fundamental and applied biological sciences. Psychology Gene expression Genes - drug effects Genes, Viral - drug effects Humans Kinetics Mammary Tumor Virus, Mouse - drug effects Mammary Tumor Virus, Mouse - genetics Mice Molecular and cellular biology Molecular genetics Plasmids Progesterone - pharmacology Promegestone - pharmacology Promoter Regions, Genetic - drug effects Repetitive Sequences, Nucleic Acid Transcription, Genetic
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