Apoptosis and Compensatory Proliferation Signaling Are Coupled by CrkI-Containing Microvesicles

Apoptosis has been implicated in compensatory proliferation signaling (CPS), whereby dying cells induce proliferation in neighboring cells as a means to restore homeostasis. The nature of signaling between apoptotic cells and their neighboring cells remains largely unknown. Here we show that a fract...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Developmental cell 2017-06, Vol.41 (6), p.674-684.e5
Hauptverfasser:	Gupta, Kajal H., Goldufsky, Josef W., Wood, Stephen J., Tardi, Nicholas J., Moorthy, Gayathri S., Gilbert, Douglas Z., Zayas, Janet P., Hahm, Eunsil, Altintas, Mehmet M., Reiser, Jochen, Shafikhani, Sasha H.
Format:	Artikel
Sprache:	eng
Schlagworte:	ACPS ACPSV Adaptor Proteins, Signal Transducing - metabolism Animals apoptosis Apoptosis - physiology apoptotic compensatory proliferation signaling apoptotic compensatory proliferation signaling vesicle c-Jun amino-terminal kinase Cell Proliferation - physiology CrkI CT10 regulator of kinase I Drosophila melanogaster - metabolism Drosophila Proteins - metabolism ExoT Exotoxin T glomerulonephritis Humans JNK JNK Mitogen-Activated Protein Kinases - metabolism nephritis nephrotoxic serum NTS Nuclear Proteins - metabolism Pseudomonas aeruginosa Signal Transduction - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!