Honokiol confers immunogenicity by dictating calreticulin exposure, activating ER stress and inhibiting epithelial-to-mesenchymal transition

Peritoneal dissemination is a major clinical obstacle in gastrointestinal cancer therapy, and it accounts for the majority of cancer-related mortality. Calreticulin (CRT) is over-expressed in gastric tumors and has been linked to poor prognosis. In this study, immunohistochemistry studies revealed t...

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Veröffentlicht in:Molecular oncology 2015-04, Vol.9 (4), p.834-849
Hauptverfasser: Liu, Shing-Hwa, Lee, Wen-Jane, Lai, De-Wei, Wu, Sheng-Mao, Liu, Chia-Yu, Tien, Hsing-Ru, Chiu, Chien-Shan, Peng, Yen-Chun, Jan, Yee-Jee, Chao, Te-Hsin, Pan, Hung-Chuan, Sheu, Meei-Ling
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Sprache:eng
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