Accumulation of miR-155 and BIC RNA in Human B Cell Lymphomas

We show that the microRNA miR-155 can be processed from sequences present in BIC RNA, a spliced and polyadenylated but non-protein-coding RNA that accumulates in lymphoma cells. The precursor of miR-155 is likely a transient spliced or unspliced nuclear BIC transcript rather than accumulated BIC RNA...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2005-03, Vol.102 (10), p.3627-3632
Hauptverfasser: Eis, Peggy S., Tam, Wayne, Sun, Liping, Chadburn, Amy, Li, Zongdong, Gomez, Mario F., Lund, Elsebet, Dahlberg, James E.
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Sprache:eng
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