A Novel Stool PCR Test for Helicobacter pylori May Predict Clarithromycin Resistance and Eradication of Infection at a High Rate

Clarithromycin-based regimens are commonly used as a first-line therapy for -positive patients; however, resistance to clarithromycin has led to treatment failures. The aim of this study was to evaluate the feasibility of using stool samples to detect the presence of DNA while concurrently detecting...

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Veröffentlicht in:	Journal of clinical microbiology 2017-08, Vol.55 (8), p.2400-2405
Hauptverfasser:	Beckman, Erin, Saracino, Ilaria, Fiorini, Giulia, Clark, Courtney, Slepnev, Vladimir, Patel, Denise, Gomez, Clarissa, Ponaka, Reddy, Elagin, Vecheslav, Vaira, Dino
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Bacteriology Clarithromycin - pharmacology DNA, Bacterial - analysis DNA, Bacterial - genetics Drug Resistance, Bacterial Feces - microbiology Helicobacter Infections - diagnosis Helicobacter Infections - microbiology Helicobacter pylori - drug effects Helicobacter pylori - isolation & purification Humans Molecular Diagnostic Techniques - methods Polymerase Chain Reaction - methods Sensitivity and Specificity
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