Effect of OPG gene mutation on protein expression and biological activity in osteoporosis

The effect of an osteoprotegerin (OPG) gene mutation was investigated on its protein expression and biological activity in osteoporosis. The pcDNA3.0-OPG plasmid or wild-type plasmid were transfected into HEK293 cells. Osteoclast tartrate-resistant acid phosphatase (TRAP) staining and counting were...

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Veröffentlicht in:	Experimental and therapeutic medicine 2017-08, Vol.14 (2), p.1475-1480
Hauptverfasser:	Qin, Shuhui, Zhang, Qiuping, Zhang, Li
Format:	Artikel
Sprache:	eng
Schlagworte:	Biotechnology Care and treatment Cell culture Disease Gene mutation Genetic aspects Genetic polymorphisms Investigations Metabolism Mutagenesis Mutation Osteoporosis polymorphism Protein expression Proteins
Online-Zugang:	Volltext
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