Claudins are essential for cell shape changes and convergent extension movements during neural tube closure

During neural tube closure, regulated changes at the level of individual cells are translated into large-scale morphogenetic movements to facilitate conversion of the flat neural plate into a closed tube. Throughout this process, the integrity of the neural epithelium is maintained via cell interact...

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Veröffentlicht in:	Developmental biology 2017-08, Vol.428 (1), p.25-38
Hauptverfasser:	Baumholtz, Amanda I., Simard, Annie, Nikolopoulou, Evanthia, Oosenbrug, Marcus, Collins, Michelle M., Piontek, Anna, Krause, Gerd, Piontek, Jörg, Greene, Nicholas D.E., Ryan, Aimee K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Cytoskeleton - metabolism Animals Apical constriction cdc42 GTP-Binding Protein - metabolism Cell Adhesion Molecules - metabolism Cell Polarity - physiology Cell Shape - physiology Chick Embryo Claudin Claudin-3 - genetics Claudin-3 - metabolism Claudin-4 - genetics Claudin-4 - metabolism Claudins - genetics Claudins - metabolism Convergent extension Embryo Culture Techniques Mice Morphogenesis - physiology Nerve Tissue Proteins - metabolism Neural Plate - embryology Neural Tube - embryology Neural tube defects Neural Tube Defects - genetics Neurulation - physiology rho GTP-Binding Proteins - metabolism Signal Transduction - physiology Tight junctions Tight Junctions - physiology
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