Obesity prevalence and related risk of comorbidities among HIV+ patients attending a New England ambulatory centre
Summary Background Human immunodeficiency virus infection and obesity are pro‐inflammatory conditions that, when occurring together, may pose a synergistic risk for diabetes and cardiovascular disease. Purpose The aim of the current study was (i) to document the prevalence of obesity in HIV+ patient...
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| Veröffentlicht in: | Obesity science & practice 2016-06, Vol.2 (2), p.123-127 |
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| container_title | Obesity science & practice |
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| creator | Becofsky, Katie M. Wing, Edward J. Wing, Rena R. Richards, Kathryn E. Gillani, Fizza S. |
| description | Summary
Background
Human immunodeficiency virus infection and obesity are pro‐inflammatory conditions that, when occurring together, may pose a synergistic risk for diabetes and cardiovascular disease.
Purpose
The aim of the current study was (i) to document the prevalence of obesity in HIV+ patients treated at the Miriam Hospital Immunology Center (Providence, RI) and (ii) to investigate the relationship between obesity and comorbidities.
Methods
The study population consisted of 1,489 HIV+ adults (70% men; average age 48 ± 11 years) treated between 01/01/2012 and 06/30/2014. Separate logistic regressions tested the associations between overweight and obesity and comorbid diagnoses (diabetes, hypertension and cardiovascular disease), as compared with normal weight. Covariates included age, gender and smoking status.
Results
Approximately 37% of patients were overweight (body mass index 25.0–29.9), and an additional 28% were obese (body mass index ≥30.0). Obesity was associated with higher odds of comorbid diabetes (OR = 3.26, CI = 1.98–5.39) and hypertension (OR = 2.11, CI = 1.49–2.98). There was no significant association between obesity and the presence of cardiovascular disease (OR = 1.12, CI = 0.66–1.90). Overweight was associated only with higher odds of comorbid diabetes (OR = 1.72; CI = 1.02–2.88).
Conclusion
Our findings demonstrate a heightened risk of comorbidities in overweight and obese HIV+ patients. Future studies should investigate whether weight loss interventions for this population can reduce cardiovascular and metabolic risk factors as they do in other populations. |
| doi_str_mv | 10.1002/osp4.38 |
| format | Article |
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Background
Human immunodeficiency virus infection and obesity are pro‐inflammatory conditions that, when occurring together, may pose a synergistic risk for diabetes and cardiovascular disease.
Purpose
The aim of the current study was (i) to document the prevalence of obesity in HIV+ patients treated at the Miriam Hospital Immunology Center (Providence, RI) and (ii) to investigate the relationship between obesity and comorbidities.
Methods
The study population consisted of 1,489 HIV+ adults (70% men; average age 48 ± 11 years) treated between 01/01/2012 and 06/30/2014. Separate logistic regressions tested the associations between overweight and obesity and comorbid diagnoses (diabetes, hypertension and cardiovascular disease), as compared with normal weight. Covariates included age, gender and smoking status.
Results
Approximately 37% of patients were overweight (body mass index 25.0–29.9), and an additional 28% were obese (body mass index ≥30.0). Obesity was associated with higher odds of comorbid diabetes (OR = 3.26, CI = 1.98–5.39) and hypertension (OR = 2.11, CI = 1.49–2.98). There was no significant association between obesity and the presence of cardiovascular disease (OR = 1.12, CI = 0.66–1.90). Overweight was associated only with higher odds of comorbid diabetes (OR = 1.72; CI = 1.02–2.88).
Conclusion
Our findings demonstrate a heightened risk of comorbidities in overweight and obese HIV+ patients. Future studies should investigate whether weight loss interventions for this population can reduce cardiovascular and metabolic risk factors as they do in other populations.</description><identifier>ISSN: 2055-2238</identifier><identifier>EISSN: 2055-2238</identifier><identifier>DOI: 10.1002/osp4.38</identifier><identifier>PMID: 28835853</identifier><language>eng</language><publisher>United States: John Wiley & Sons, Inc</publisher><subject>Acquired immune deficiency syndrome ; AIDS ; Body mass index ; Body weight ; Body weight loss ; Cardiovascular diseases ; Comorbidity ; Demographics ; Diabetes mellitus ; HIV ; Human immunodeficiency virus ; Hypertension ; Inflammation ; Obesity ; Original ; Overweight ; Population studies ; Risk factors ; Smoking ; Studies</subject><ispartof>Obesity science & practice, 2016-06, Vol.2 (2), p.123-127</ispartof><rights>2016 The Authors. Obesity Science & Practice published by John Wiley & Sons Ltd, World Obesity and The Obesity Society.</rights><rights>2016. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4618-293fa99635c1a417509878d32b147c52028651666adb69aa7527af31b07f2a5b3</citedby><cites>FETCH-LOGICAL-c4618-293fa99635c1a417509878d32b147c52028651666adb69aa7527af31b07f2a5b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523689/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523689/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,865,886,1418,11567,27929,27930,45579,45580,46057,46481,53796,53798</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28835853$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Becofsky, Katie M.</creatorcontrib><creatorcontrib>Wing, Edward J.</creatorcontrib><creatorcontrib>Wing, Rena R.</creatorcontrib><creatorcontrib>Richards, Kathryn E.</creatorcontrib><creatorcontrib>Gillani, Fizza S.</creatorcontrib><title>Obesity prevalence and related risk of comorbidities among HIV+ patients attending a New England ambulatory centre</title><title>Obesity science & practice</title><addtitle>Obes Sci Pract</addtitle><description>Summary
Background
Human immunodeficiency virus infection and obesity are pro‐inflammatory conditions that, when occurring together, may pose a synergistic risk for diabetes and cardiovascular disease.
Purpose
The aim of the current study was (i) to document the prevalence of obesity in HIV+ patients treated at the Miriam Hospital Immunology Center (Providence, RI) and (ii) to investigate the relationship between obesity and comorbidities.
Methods
The study population consisted of 1,489 HIV+ adults (70% men; average age 48 ± 11 years) treated between 01/01/2012 and 06/30/2014. Separate logistic regressions tested the associations between overweight and obesity and comorbid diagnoses (diabetes, hypertension and cardiovascular disease), as compared with normal weight. Covariates included age, gender and smoking status.
Results
Approximately 37% of patients were overweight (body mass index 25.0–29.9), and an additional 28% were obese (body mass index ≥30.0). Obesity was associated with higher odds of comorbid diabetes (OR = 3.26, CI = 1.98–5.39) and hypertension (OR = 2.11, CI = 1.49–2.98). There was no significant association between obesity and the presence of cardiovascular disease (OR = 1.12, CI = 0.66–1.90). Overweight was associated only with higher odds of comorbid diabetes (OR = 1.72; CI = 1.02–2.88).
Conclusion
Our findings demonstrate a heightened risk of comorbidities in overweight and obese HIV+ patients. Future studies should investigate whether weight loss interventions for this population can reduce cardiovascular and metabolic risk factors as they do in other populations.</description><subject>Acquired immune deficiency syndrome</subject><subject>AIDS</subject><subject>Body mass index</subject><subject>Body weight</subject><subject>Body weight loss</subject><subject>Cardiovascular diseases</subject><subject>Comorbidity</subject><subject>Demographics</subject><subject>Diabetes mellitus</subject><subject>HIV</subject><subject>Human immunodeficiency virus</subject><subject>Hypertension</subject><subject>Inflammation</subject><subject>Obesity</subject><subject>Original</subject><subject>Overweight</subject><subject>Population studies</subject><subject>Risk factors</subject><subject>Smoking</subject><subject>Studies</subject><issn>2055-2238</issn><issn>2055-2238</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>WIN</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kV1LHTEQhkOpqKj4D0qgFy3I0XxssslNoYitgniEftyG2d3Z09jdzTbZVc6_b06PFVvwasLMw5MZXkKOOTvljImzkMbiVJpXZF8wpRZCSPP62XuPHKV0xxjjymou-C7ZE8ZIZZTcJ3FZYfLTmo4R76HDoUYKQ0MjdjBhrj79pKGldehDrHzjJ4-JQh-GFb28-n5CR8idYcq9acKh8bkP9AYf6MWw6jYm6Ks5u0Jc0zqDEQ_JTgtdwqPHekC-fbr4en65uF5-vjr_eL2oC83NQljZgrVaqppDwUvFrClNI0XFi7JWggmjFddaQ1NpC1AqUUIrecXKVoCq5AH5sPWOc9Vj8-dz6NwYfQ9x7QJ49-9k8D_cKtw7pYTUxmbB-0dBDL9mTJPrfaqxy2dhmJPjVgqujdYqo2__Q-_CHId8nhPC2FJIrnmm3m2pOoaUIrZPy3DmNlG6TZROmky-eb77E_c3uAycbIEH3-H6JY9bfrktsu43UgCniA</recordid><startdate>201606</startdate><enddate>201606</enddate><creator>Becofsky, Katie M.</creator><creator>Wing, Edward J.</creator><creator>Wing, Rena R.</creator><creator>Richards, Kathryn E.</creator><creator>Gillani, Fizza S.</creator><general>John Wiley & Sons, Inc</general><general>John Wiley and Sons Inc</general><scope>24P</scope><scope>WIN</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FE</scope><scope>8FH</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201606</creationdate><title>Obesity prevalence and related risk of comorbidities among HIV+ patients attending a New England ambulatory centre</title><author>Becofsky, Katie M. ; Wing, Edward J. ; Wing, Rena R. ; Richards, Kathryn E. ; Gillani, Fizza S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4618-293fa99635c1a417509878d32b147c52028651666adb69aa7527af31b07f2a5b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Acquired immune deficiency syndrome</topic><topic>AIDS</topic><topic>Body mass index</topic><topic>Body weight</topic><topic>Body weight loss</topic><topic>Cardiovascular diseases</topic><topic>Comorbidity</topic><topic>Demographics</topic><topic>Diabetes mellitus</topic><topic>HIV</topic><topic>Human immunodeficiency virus</topic><topic>Hypertension</topic><topic>Inflammation</topic><topic>Obesity</topic><topic>Original</topic><topic>Overweight</topic><topic>Population studies</topic><topic>Risk factors</topic><topic>Smoking</topic><topic>Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Becofsky, Katie M.</creatorcontrib><creatorcontrib>Wing, Edward J.</creatorcontrib><creatorcontrib>Wing, Rena R.</creatorcontrib><creatorcontrib>Richards, Kathryn E.</creatorcontrib><creatorcontrib>Gillani, Fizza S.</creatorcontrib><collection>Wiley Online Library (Open Access Collection)</collection><collection>Wiley Online Library (Open Access Collection)</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection (ProQuest)</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Biological Science Database</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Obesity science & practice</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Becofsky, Katie M.</au><au>Wing, Edward J.</au><au>Wing, Rena R.</au><au>Richards, Kathryn E.</au><au>Gillani, Fizza S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Obesity prevalence and related risk of comorbidities among HIV+ patients attending a New England ambulatory centre</atitle><jtitle>Obesity science & practice</jtitle><addtitle>Obes Sci Pract</addtitle><date>2016-06</date><risdate>2016</risdate><volume>2</volume><issue>2</issue><spage>123</spage><epage>127</epage><pages>123-127</pages><issn>2055-2238</issn><eissn>2055-2238</eissn><abstract>Summary
Background
Human immunodeficiency virus infection and obesity are pro‐inflammatory conditions that, when occurring together, may pose a synergistic risk for diabetes and cardiovascular disease.
Purpose
The aim of the current study was (i) to document the prevalence of obesity in HIV+ patients treated at the Miriam Hospital Immunology Center (Providence, RI) and (ii) to investigate the relationship between obesity and comorbidities.
Methods
The study population consisted of 1,489 HIV+ adults (70% men; average age 48 ± 11 years) treated between 01/01/2012 and 06/30/2014. Separate logistic regressions tested the associations between overweight and obesity and comorbid diagnoses (diabetes, hypertension and cardiovascular disease), as compared with normal weight. Covariates included age, gender and smoking status.
Results
Approximately 37% of patients were overweight (body mass index 25.0–29.9), and an additional 28% were obese (body mass index ≥30.0). Obesity was associated with higher odds of comorbid diabetes (OR = 3.26, CI = 1.98–5.39) and hypertension (OR = 2.11, CI = 1.49–2.98). There was no significant association between obesity and the presence of cardiovascular disease (OR = 1.12, CI = 0.66–1.90). Overweight was associated only with higher odds of comorbid diabetes (OR = 1.72; CI = 1.02–2.88).
Conclusion
Our findings demonstrate a heightened risk of comorbidities in overweight and obese HIV+ patients. Future studies should investigate whether weight loss interventions for this population can reduce cardiovascular and metabolic risk factors as they do in other populations.</abstract><cop>United States</cop><pub>John Wiley & Sons, Inc</pub><pmid>28835853</pmid><doi>10.1002/osp4.38</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| source | DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; Wiley Online Library All Journals; Wiley Online Library (Open Access Collection); PubMed Central |
| subjects | Acquired immune deficiency syndrome AIDS Body mass index Body weight Body weight loss Cardiovascular diseases Comorbidity Demographics Diabetes mellitus HIV Human immunodeficiency virus Hypertension Inflammation Obesity Original Overweight Population studies Risk factors Smoking Studies |
| title | Obesity prevalence and related risk of comorbidities among HIV+ patients attending a New England ambulatory centre |
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