Reduced brain UCP2 expression mediated by microRNA-503 contributes to increased stroke susceptibility in the high-salt fed stroke-prone spontaneously hypertensive rat

UCP2 maps nearby the lod score peak of STR1 -stroke QTL in the SHRSP rat strain. We explored the potential contribution of UCP2 to the high-salt diet (JD)-dependent increased stroke susceptibility of SHRSP. Male SHRSP, SHRSR, two reciprocal SHRSR/SHRSP- STR1/ QTL stroke congenic lines received JD fo...

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Veröffentlicht in:Cell death & disease 2017-06, Vol.8 (6), p.e2891-e2891
Hauptverfasser: Rubattu, Speranza, Stanzione, Rosita, Bianchi, Franca, Cotugno, Maria, Forte, Maurizio, Della Ragione, Floriana, Fioriniello, Salvatore, D'Esposito, Maurizio, Marchitti, Simona, Madonna, Michele, Baima, Simona, Morelli, Giorgio, Sciarretta, Sebastiano, Sironi, Luigi, Gelosa, Paolo, Volpe, Massimo
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Sprache:eng
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