Arterial Stiffening With Exercise in Patients With Heart Failure and Preserved Ejection Fraction

Aortic stiffening and reduced nitric oxide (NO) availability may contribute to the pathophysiology of heart failure with preserved ejection fraction (HFpEF). This study compared indices of arterial stiffness at rest and during exercise in subjects with HFpEF and hypertensive control subjects to exam...

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Veröffentlicht in:	Journal of the American College of Cardiology 2017-07, Vol.70 (2), p.136-148
Hauptverfasser:	Reddy, Yogesh N.V., Andersen, Mads J., Obokata, Masaru, Koepp, Katlyn E., Kane, Garvan C., Melenovsky, Vojtech, Olson, Thomas P., Borlaug, Barry A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute effects Aged Aging Aorta aortic stiffness Blood pressure Cardiac output Cardiology Cardiovascular disease Correlation Double-Blind Method Dyspnea exercise Exercise - physiology Exercise Test Female Gas analysis Heart diseases Heart failure Heart Failure - drug therapy Heart Failure - physiopathology Heart function Heart rate Hemodynamics HFpEF Humans Hypertension Intubation Lung diseases Male Middle Aged Nitrates - pharmacology Nitric oxide Nitrites Obesity Oxygen consumption Patients Prospective Studies Pulmonary arteries Rest - physiology Sodium Sodium nitrite Stroke Stroke Volume - physiology Studies Vascular Stiffness - physiology Ventricle Ventricular Function, Left - physiology Wave reflection Wave resistance Waveform analysis Waveforms
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