Ischemic priapism: Can eosinophil count and platelet functions be positive predictive factors in etiopathogenesis

Ischemic priapism: Can eosinophil count and platelet functions be positive predictive factors in etiopathogenesis

We evaluated the relation between ischemic priapism (IP) and blood count parameters in IP patients. We especially wanted to examine the contribution of eosinophil count (EC), platelet count (PC), and mean platelet volume (MPV) values, which are suspected predictive parameters for vascular endotheliu...

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Veröffentlicht in:Canadian Urological Association journal 2017-07, Vol.11 (7), p.E297-301
Hauptverfasser: Sönmez, Mehmet Giray, Kara, Cengiz, Karaibrahimoğlu, Adnan, Sönmez, Leyla Öztürk, Göğer, Yunus Emre, Balasar, Mehmet, Taşkapu, Hakki Hakan, Pişkin, Mehmet Mesut, Öztürk, Ahmet, Kilinç, Mehmet
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container_end_page 301
container_issue 7
container_start_page E297
container_title Canadian Urological Association journal
container_volume 11
creator Sönmez, Mehmet Giray
Kara, Cengiz
Karaibrahimoğlu, Adnan
Sönmez, Leyla Öztürk
Göğer, Yunus Emre
Balasar, Mehmet
Taşkapu, Hakki Hakan
Pişkin, Mehmet Mesut
Öztürk, Ahmet
Kilinç, Mehmet
description We evaluated the relation between ischemic priapism (IP) and blood count parameters in IP patients. We especially wanted to examine the contribution of eosinophil count (EC), platelet count (PC), and mean platelet volume (MPV) values, which are suspected predictive parameters for vascular endothelium damage and venoocclusive pathogenesis and etiopathogenesis, particularly in IP. A total of 40 IP patients fulfilled the study criteria. Forty healthy volunteers in a similar age group were included as the control group. Complete blood count values were compared between the two groups. Intergroup comparisons were performed using the Mann-Whitney U test, and the chi-square test was used to assess the relationship between categorical variables in the patient groups. The area under the curve was calculated by receiver operating characteristic (ROC) regression analyses. Epidemiological diagnosis percentages were calculated by finding cutoff values. The IP group's high MPV, PC, and EC values compared to those of the control group were detected to be statistically significant (p
doi_str_mv 10.5489/cuaj.4263
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We especially wanted to examine the contribution of eosinophil count (EC), platelet count (PC), and mean platelet volume (MPV) values, which are suspected predictive parameters for vascular endothelium damage and venoocclusive pathogenesis and etiopathogenesis, particularly in IP. A total of 40 IP patients fulfilled the study criteria. Forty healthy volunteers in a similar age group were included as the control group. Complete blood count values were compared between the two groups. Intergroup comparisons were performed using the Mann-Whitney U test, and the chi-square test was used to assess the relationship between categorical variables in the patient groups. The area under the curve was calculated by receiver operating characteristic (ROC) regression analyses. Epidemiological diagnosis percentages were calculated by finding cutoff values. The IP group's high MPV, PC, and EC values compared to those of the control group were detected to be statistically significant (p&lt;0.001, p=0,03, p=0.001, respectively). No statistically significant difference was observed between the two groups for other blood count parameters. Statistically significant values for IP were measured as MPV: positive predictive value: 84%; EC: positive predictive value: 71.4%; and PC: positive predictive value: 61.4%. High MPV, PC, and EC values are significant positive predictive factors in IP etiopathogenesis. 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We especially wanted to examine the contribution of eosinophil count (EC), platelet count (PC), and mean platelet volume (MPV) values, which are suspected predictive parameters for vascular endothelium damage and venoocclusive pathogenesis and etiopathogenesis, particularly in IP. A total of 40 IP patients fulfilled the study criteria. Forty healthy volunteers in a similar age group were included as the control group. Complete blood count values were compared between the two groups. Intergroup comparisons were performed using the Mann-Whitney U test, and the chi-square test was used to assess the relationship between categorical variables in the patient groups. The area under the curve was calculated by receiver operating characteristic (ROC) regression analyses. Epidemiological diagnosis percentages were calculated by finding cutoff values. The IP group's high MPV, PC, and EC values compared to those of the control group were detected to be statistically significant (p&lt;0.001, p=0,03, p=0.001, respectively). No statistically significant difference was observed between the two groups for other blood count parameters. Statistically significant values for IP were measured as MPV: positive predictive value: 84%; EC: positive predictive value: 71.4%; and PC: positive predictive value: 61.4%. High MPV, PC, and EC values are significant positive predictive factors in IP etiopathogenesis. 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We especially wanted to examine the contribution of eosinophil count (EC), platelet count (PC), and mean platelet volume (MPV) values, which are suspected predictive parameters for vascular endothelium damage and venoocclusive pathogenesis and etiopathogenesis, particularly in IP. A total of 40 IP patients fulfilled the study criteria. Forty healthy volunteers in a similar age group were included as the control group. Complete blood count values were compared between the two groups. Intergroup comparisons were performed using the Mann-Whitney U test, and the chi-square test was used to assess the relationship between categorical variables in the patient groups. The area under the curve was calculated by receiver operating characteristic (ROC) regression analyses. Epidemiological diagnosis percentages were calculated by finding cutoff values. The IP group's high MPV, PC, and EC values compared to those of the control group were detected to be statistically significant (p&lt;0.001, p=0,03, p=0.001, respectively). No statistically significant difference was observed between the two groups for other blood count parameters. Statistically significant values for IP were measured as MPV: positive predictive value: 84%; EC: positive predictive value: 71.4%; and PC: positive predictive value: 61.4%. High MPV, PC, and EC values are significant positive predictive factors in IP etiopathogenesis. No proof was detected for other blood count parameters playing an active role in IP etiopathogenesis.</abstract><cop>Canada</cop><pub>Canadian Medical Association</pub><pmid>28761591</pmid><doi>10.5489/cuaj.4263</doi><oa>free_for_read</oa></addata></record>
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title Ischemic priapism: Can eosinophil count and platelet functions be positive predictive factors in etiopathogenesis
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