Surgical management of malignant glaucoma: a retrospective analysis of fifty eight eyes
Purpose To assess outcomes of surgical management of malignant glaucoma in terms of re-formation of anterior chamber Methods This was a retrospective analysis of consecutive patients who underwent surgical treatment for malignant glaucoma between January 1995 and December 2013 at a tertiary care oph...
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| Veröffentlicht in: | Eye (London) 2017-06, Vol.31 (6), p.947-955 |
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| creator | Balekudaru, S Choudhari, N S Rewri, P George, R Bhende, P S Bhende, M Lingam, V Lingam, G |
| description | Purpose
To assess outcomes of surgical management of malignant glaucoma in terms of re-formation of anterior chamber
Methods
This was a retrospective analysis of consecutive patients who underwent surgical treatment for malignant glaucoma between January 1995 and December 2013 at a tertiary care ophthalmic institute, with a minimum follow up of 2 months.
Results
Fifty eight eyes of 58 patients were included. Fifty two (89.7%) patients had primary angle closure glaucoma. The majority had undergone glaucoma filtration surgery earlier (
n
=53, 91.4%). Lensectomy and anterior vitrectomy was performed in 15 (25.9%) eyes (Group 1). Vitrectomy and anterior chamber re-formation was performed in 27 (46.6%) eyes (Group 2). Vitrectomy-phacoemulsification-vitrectomy was performed in 16 (27.6%) eyes (Group 3). Communication between the two segments of eye through anterior hyaloid, lens capsule complex and/or iris was achieved in all groups. The median follow-up (Inter-quartile range) was 30 (71.5) months. Anterior chamber re-formation was achieved in 56 (96.5%) eyes at final visit. The improvement in mean±SD LogMAR visual acuity (1.1±1 to 0.7±0.8) and reduction in number ±SD of anti-glaucoma medications (2.1±1.1 to 1±1.6) between onset and final visit were significant (
P
=0.02 and |
| doi_str_mv | 10.1038/eye.2017.32 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5518837</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>4322751423</sourcerecordid><originalsourceid>FETCH-LOGICAL-c549t-9eae568658b2cd0a3221e7cf278fa4b45d572a099612d2fe32f5a50403ff1053</originalsourceid><addsrcrecordid>eNqFkc1r3DAQxUVJaTbbnHovhlwCqbfSyLKkHAIl9AsCOSTQ3IRWO3IU_LGV7MD-95XZNKSlUF3E8H56M3pDyDtGV4xy9RF3uALK5IrDK7JglaxLUYnqgCyoFrQEgLtDcpTSA6VZlPQNOQQFQjJeL8iPmyk2wdm26GxvG-ywH4vB56oNTW9z0bR2ckNnzwtbRBzjkLboxvCIRX7Q7lJIM--DH3cFhuZ-LPJA6S157W2b8PjpXpLbL59vL7-VV9dfv19-uiqdqPRYarQoalULtQa3oZYDMJTOg1TeVutKbIQES7WuGWzAIwcvrKAV5d4zKviSXOxtt9O6w43L00fbmm0MnY07M9hg_lT6cG-a4dEIwZTiMhucPhnE4eeEaTRdSA7b1vY4TMkwzVjNNOS0_osqWc0n-y7JyV_owzDFHNdsSGulqRQ6U2d7yuVQU0T_PDejZl6tyUmaebWGQ6bfv_zqM_t7lxn4sAdSlvoG44um__D7BTybrmM</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1906890759</pqid></control><display><type>article</type><title>Surgical management of malignant glaucoma: a retrospective analysis of fifty eight eyes</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Balekudaru, S ; Choudhari, N S ; Rewri, P ; George, R ; Bhende, P S ; Bhende, M ; Lingam, V ; Lingam, G</creator><creatorcontrib>Balekudaru, S ; Choudhari, N S ; Rewri, P ; George, R ; Bhende, P S ; Bhende, M ; Lingam, V ; Lingam, G</creatorcontrib><description>Purpose
To assess outcomes of surgical management of malignant glaucoma in terms of re-formation of anterior chamber
Methods
This was a retrospective analysis of consecutive patients who underwent surgical treatment for malignant glaucoma between January 1995 and December 2013 at a tertiary care ophthalmic institute, with a minimum follow up of 2 months.
Results
Fifty eight eyes of 58 patients were included. Fifty two (89.7%) patients had primary angle closure glaucoma. The majority had undergone glaucoma filtration surgery earlier (
n
=53, 91.4%). Lensectomy and anterior vitrectomy was performed in 15 (25.9%) eyes (Group 1). Vitrectomy and anterior chamber re-formation was performed in 27 (46.6%) eyes (Group 2). Vitrectomy-phacoemulsification-vitrectomy was performed in 16 (27.6%) eyes (Group 3). Communication between the two segments of eye through anterior hyaloid, lens capsule complex and/or iris was achieved in all groups. The median follow-up (Inter-quartile range) was 30 (71.5) months. Anterior chamber re-formation was achieved in 56 (96.5%) eyes at final visit. The improvement in mean±SD LogMAR visual acuity (1.1±1 to 0.7±0.8) and reduction in number ±SD of anti-glaucoma medications (2.1±1.1 to 1±1.6) between onset and final visit were significant (
P
=0.02 and <0.01, respectively). The intraocular pressure (mm Hg) at onset and at final visit was 30.7±17.4 and 14±6.2, 32.8±12.6 and 15.3±7.4, and 27.2±14 and 10.9±3 in groups 1–3, respectively (all
P
<0.01).
Conclusion
Our anatomical success rate was high. The key element in achieving this outcome was the establishment of a patent communication between the vitreous cavity and the anterior chamber.</description><identifier>ISSN: 0950-222X</identifier><identifier>EISSN: 1476-5454</identifier><identifier>DOI: 10.1038/eye.2017.32</identifier><identifier>PMID: 28257136</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>692/308/409 ; 692/699/3161 ; Adolescent ; Adult ; Aged ; Anterior Chamber - diagnostic imaging ; Clinical Study ; Female ; Glaucoma ; Glaucoma - diagnosis ; Glaucoma - physiopathology ; Glaucoma - surgery ; Humans ; Intraocular Pressure ; Laboratory Medicine ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Ophthalmology ; Ophthalmoscopy ; Phacoemulsification - methods ; Pharmaceutical Sciences/Technology ; Retrospective Studies ; Severity of Illness Index ; Surgery ; Surgical Oncology ; Treatment Outcome ; Ultrasonography ; Visual Acuity ; Vitrectomy - methods ; Young Adult</subject><ispartof>Eye (London), 2017-06, Vol.31 (6), p.947-955</ispartof><rights>Royal College of Ophthalmologists Macmillan Publishers Limited, part of Springer Nature. 2017</rights><rights>Copyright Nature Publishing Group Jun 2017</rights><rights>Copyright © 2017 Royal College of Ophthalmologists Macmillan Publishers Limited, part of Springer Nature. 2017 Royal College of Ophthalmologists Macmillan Publishers Limited, part of Springer Nature.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c549t-9eae568658b2cd0a3221e7cf278fa4b45d572a099612d2fe32f5a50403ff1053</citedby><cites>FETCH-LOGICAL-c549t-9eae568658b2cd0a3221e7cf278fa4b45d572a099612d2fe32f5a50403ff1053</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518837/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518837/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28257136$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Balekudaru, S</creatorcontrib><creatorcontrib>Choudhari, N S</creatorcontrib><creatorcontrib>Rewri, P</creatorcontrib><creatorcontrib>George, R</creatorcontrib><creatorcontrib>Bhende, P S</creatorcontrib><creatorcontrib>Bhende, M</creatorcontrib><creatorcontrib>Lingam, V</creatorcontrib><creatorcontrib>Lingam, G</creatorcontrib><title>Surgical management of malignant glaucoma: a retrospective analysis of fifty eight eyes</title><title>Eye (London)</title><addtitle>Eye</addtitle><addtitle>Eye (Lond)</addtitle><description>Purpose
To assess outcomes of surgical management of malignant glaucoma in terms of re-formation of anterior chamber
Methods
This was a retrospective analysis of consecutive patients who underwent surgical treatment for malignant glaucoma between January 1995 and December 2013 at a tertiary care ophthalmic institute, with a minimum follow up of 2 months.
Results
Fifty eight eyes of 58 patients were included. Fifty two (89.7%) patients had primary angle closure glaucoma. The majority had undergone glaucoma filtration surgery earlier (
n
=53, 91.4%). Lensectomy and anterior vitrectomy was performed in 15 (25.9%) eyes (Group 1). Vitrectomy and anterior chamber re-formation was performed in 27 (46.6%) eyes (Group 2). Vitrectomy-phacoemulsification-vitrectomy was performed in 16 (27.6%) eyes (Group 3). Communication between the two segments of eye through anterior hyaloid, lens capsule complex and/or iris was achieved in all groups. The median follow-up (Inter-quartile range) was 30 (71.5) months. Anterior chamber re-formation was achieved in 56 (96.5%) eyes at final visit. The improvement in mean±SD LogMAR visual acuity (1.1±1 to 0.7±0.8) and reduction in number ±SD of anti-glaucoma medications (2.1±1.1 to 1±1.6) between onset and final visit were significant (
P
=0.02 and <0.01, respectively). The intraocular pressure (mm Hg) at onset and at final visit was 30.7±17.4 and 14±6.2, 32.8±12.6 and 15.3±7.4, and 27.2±14 and 10.9±3 in groups 1–3, respectively (all
P
<0.01).
Conclusion
Our anatomical success rate was high. The key element in achieving this outcome was the establishment of a patent communication between the vitreous cavity and the anterior chamber.</description><subject>692/308/409</subject><subject>692/699/3161</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Anterior Chamber - diagnostic imaging</subject><subject>Clinical Study</subject><subject>Female</subject><subject>Glaucoma</subject><subject>Glaucoma - diagnosis</subject><subject>Glaucoma - physiopathology</subject><subject>Glaucoma - surgery</subject><subject>Humans</subject><subject>Intraocular Pressure</subject><subject>Laboratory Medicine</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Ophthalmology</subject><subject>Ophthalmoscopy</subject><subject>Phacoemulsification - methods</subject><subject>Pharmaceutical Sciences/Technology</subject><subject>Retrospective Studies</subject><subject>Severity of Illness Index</subject><subject>Surgery</subject><subject>Surgical Oncology</subject><subject>Treatment Outcome</subject><subject>Ultrasonography</subject><subject>Visual Acuity</subject><subject>Vitrectomy - methods</subject><subject>Young Adult</subject><issn>0950-222X</issn><issn>1476-5454</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkc1r3DAQxUVJaTbbnHovhlwCqbfSyLKkHAIl9AsCOSTQ3IRWO3IU_LGV7MD-95XZNKSlUF3E8H56M3pDyDtGV4xy9RF3uALK5IrDK7JglaxLUYnqgCyoFrQEgLtDcpTSA6VZlPQNOQQFQjJeL8iPmyk2wdm26GxvG-ywH4vB56oNTW9z0bR2ckNnzwtbRBzjkLboxvCIRX7Q7lJIM--DH3cFhuZ-LPJA6S157W2b8PjpXpLbL59vL7-VV9dfv19-uiqdqPRYarQoalULtQa3oZYDMJTOg1TeVutKbIQES7WuGWzAIwcvrKAV5d4zKviSXOxtt9O6w43L00fbmm0MnY07M9hg_lT6cG-a4dEIwZTiMhucPhnE4eeEaTRdSA7b1vY4TMkwzVjNNOS0_osqWc0n-y7JyV_owzDFHNdsSGulqRQ6U2d7yuVQU0T_PDejZl6tyUmaebWGQ6bfv_zqM_t7lxn4sAdSlvoG44um__D7BTybrmM</recordid><startdate>20170601</startdate><enddate>20170601</enddate><creator>Balekudaru, S</creator><creator>Choudhari, N S</creator><creator>Rewri, P</creator><creator>George, R</creator><creator>Bhende, P S</creator><creator>Bhende, M</creator><creator>Lingam, V</creator><creator>Lingam, G</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20170601</creationdate><title>Surgical management of malignant glaucoma: a retrospective analysis of fifty eight eyes</title><author>Balekudaru, S ; Choudhari, N S ; Rewri, P ; George, R ; Bhende, P S ; Bhende, M ; Lingam, V ; Lingam, G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c549t-9eae568658b2cd0a3221e7cf278fa4b45d572a099612d2fe32f5a50403ff1053</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>692/308/409</topic><topic>692/699/3161</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Anterior Chamber - diagnostic imaging</topic><topic>Clinical Study</topic><topic>Female</topic><topic>Glaucoma</topic><topic>Glaucoma - diagnosis</topic><topic>Glaucoma - physiopathology</topic><topic>Glaucoma - surgery</topic><topic>Humans</topic><topic>Intraocular Pressure</topic><topic>Laboratory Medicine</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Ophthalmology</topic><topic>Ophthalmoscopy</topic><topic>Phacoemulsification - methods</topic><topic>Pharmaceutical Sciences/Technology</topic><topic>Retrospective Studies</topic><topic>Severity of Illness Index</topic><topic>Surgery</topic><topic>Surgical Oncology</topic><topic>Treatment Outcome</topic><topic>Ultrasonography</topic><topic>Visual Acuity</topic><topic>Vitrectomy - methods</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Balekudaru, S</creatorcontrib><creatorcontrib>Choudhari, N S</creatorcontrib><creatorcontrib>Rewri, P</creatorcontrib><creatorcontrib>George, R</creatorcontrib><creatorcontrib>Bhende, P S</creatorcontrib><creatorcontrib>Bhende, M</creatorcontrib><creatorcontrib>Lingam, V</creatorcontrib><creatorcontrib>Lingam, G</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Eye (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Balekudaru, S</au><au>Choudhari, N S</au><au>Rewri, P</au><au>George, R</au><au>Bhende, P S</au><au>Bhende, M</au><au>Lingam, V</au><au>Lingam, G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Surgical management of malignant glaucoma: a retrospective analysis of fifty eight eyes</atitle><jtitle>Eye (London)</jtitle><stitle>Eye</stitle><addtitle>Eye (Lond)</addtitle><date>2017-06-01</date><risdate>2017</risdate><volume>31</volume><issue>6</issue><spage>947</spage><epage>955</epage><pages>947-955</pages><issn>0950-222X</issn><eissn>1476-5454</eissn><abstract>Purpose
To assess outcomes of surgical management of malignant glaucoma in terms of re-formation of anterior chamber
Methods
This was a retrospective analysis of consecutive patients who underwent surgical treatment for malignant glaucoma between January 1995 and December 2013 at a tertiary care ophthalmic institute, with a minimum follow up of 2 months.
Results
Fifty eight eyes of 58 patients were included. Fifty two (89.7%) patients had primary angle closure glaucoma. The majority had undergone glaucoma filtration surgery earlier (
n
=53, 91.4%). Lensectomy and anterior vitrectomy was performed in 15 (25.9%) eyes (Group 1). Vitrectomy and anterior chamber re-formation was performed in 27 (46.6%) eyes (Group 2). Vitrectomy-phacoemulsification-vitrectomy was performed in 16 (27.6%) eyes (Group 3). Communication between the two segments of eye through anterior hyaloid, lens capsule complex and/or iris was achieved in all groups. The median follow-up (Inter-quartile range) was 30 (71.5) months. Anterior chamber re-formation was achieved in 56 (96.5%) eyes at final visit. The improvement in mean±SD LogMAR visual acuity (1.1±1 to 0.7±0.8) and reduction in number ±SD of anti-glaucoma medications (2.1±1.1 to 1±1.6) between onset and final visit were significant (
P
=0.02 and <0.01, respectively). The intraocular pressure (mm Hg) at onset and at final visit was 30.7±17.4 and 14±6.2, 32.8±12.6 and 15.3±7.4, and 27.2±14 and 10.9±3 in groups 1–3, respectively (all
P
<0.01).
Conclusion
Our anatomical success rate was high. The key element in achieving this outcome was the establishment of a patent communication between the vitreous cavity and the anterior chamber.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>28257136</pmid><doi>10.1038/eye.2017.32</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Eye (London), 2017-06, Vol.31 (6), p.947-955 |
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| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | 692/308/409 692/699/3161 Adolescent Adult Aged Anterior Chamber - diagnostic imaging Clinical Study Female Glaucoma Glaucoma - diagnosis Glaucoma - physiopathology Glaucoma - surgery Humans Intraocular Pressure Laboratory Medicine Male Medicine Medicine & Public Health Middle Aged Ophthalmology Ophthalmoscopy Phacoemulsification - methods Pharmaceutical Sciences/Technology Retrospective Studies Severity of Illness Index Surgery Surgical Oncology Treatment Outcome Ultrasonography Visual Acuity Vitrectomy - methods Young Adult |
| title | Surgical management of malignant glaucoma: a retrospective analysis of fifty eight eyes |
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