Deficiens, a homeotic gene involved in the control of flower morphogenesis in Antirrhinum majus: the protein shows homology to transcription factors
Deficiens (defA+) is a homeotic gene involved in the genetic control of Antirrhinum majus flower development. Mutation of this gene (defA‐1) causes homeotic transformation of petals into sepals and of stamina into carpels in flowers displaying the ‘globifera’ phenotype, as shown by cross sections an...
Gespeichert in:
| Veröffentlicht in: | The EMBO journal 1990-03, Vol.9 (3), p.605-613 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 613 |
|---|---|
| container_issue | 3 |
| container_start_page | 605 |
| container_title | The EMBO journal |
| container_volume | 9 |
| creator | Sommer, H. Beltrán, J.P. Huijser, P. Pape, H. Lönnig, W.E. Saedler, H. Schwarz‐Sommer, Z. |
| description | Deficiens (defA+) is a homeotic gene involved in the genetic control of Antirrhinum majus flower development. Mutation of this gene (defA‐1) causes homeotic transformation of petals into sepals and of stamina into carpels in flowers displaying the ‘globifera’ phenotype, as shown by cross sections and scanning electronmicroscopy of developing flowers. A cDNA derived from the wild type defA+ gene has been cloned by differential screening of a subtracted ‘flower specific’ cDNA library. The identity of this cDNA with the defA+ gene product has been confirmed by utilizing the somatic and germinal instability of defA‐1 mutants. According to Northern blot analyses the defA+ gene is expressed in flowers but not in leaves, and its expression is nearly constant during all stages of flower development. The 1.1 kb long mRNA has a 681 bp long open reading frame that can code for a putative protein of 227 amino acids (mol. wt 26.2 kd). At its N‐terminus the DEF A protein reveals homology to a conserved domain of the regulatory proteins SRF (activating c‐fos) in mammals and GRM/PRTF (regulating mating type) in yeast. We discuss the structure and the possible function of the DEF A protein in the control of floral organogenesis. |
| doi_str_mv | 10.1002/j.1460-2075.1990.tb08152.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_551713</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>79668492</sourcerecordid><originalsourceid>FETCH-LOGICAL-c6042-98b793ec3a8167255b1cde54d6af32931d2779a6371d9cdbe6a197d26df9e06f3</originalsourceid><addsrcrecordid>eNqVkcuO0zAUhiMEGjoDj4BkIcSKFjsXX0ZiUYbhpkFsYG05zknjKsnp2E47fY95YJJpVWCFWNnS__32sb8kecnoglGavl0vWM7pPKWiWDCl6CKWVLIiXdw9Sman6HEyoyln85xJ9TQ5D2FNKS2kYGfJGVNcyozOkvsPUDvroA9viCENdoDRWbKCHojrt9huoRo3JDZALPbRY0uwJnWLO_CkQ79pcIKDCxO27KPzvnH90JHOrIdw-dDceIwwxqHBXZhuwRZXexKRRG_6YL3bRIc9qY2N6MOz5Elt2gDPj-tF8vPj9Y-rz_Ob75--XC1v5pbTPJ0rWQqVgc2MZFykRVEyW0GRV9zUWaoyVqVCKMMzwSplqxK4YUpUKa9qBZTX2UXy7nDuZig7qCyM7zOt3njXGb_XaJz-O-ldo1e41UXBBMvG_utj3-PtACHqzgULbWt6wCFooTiXuUr_CbJCqmz0NoKXB9B6DMFDfRqGUT2512s9CdaTYD2510f3-m4sv_jzOb-rB9lj_uqYm2BNW49fb104YVzSnAk5YssDtnMt7P9jAH397f3Xh332CyY00TU</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>15893460</pqid></control><display><type>article</type><title>Deficiens, a homeotic gene involved in the control of flower morphogenesis in Antirrhinum majus: the protein shows homology to transcription factors</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><source>Free Full-Text Journals in Chemistry</source><creator>Sommer, H. ; Beltrán, J.P. ; Huijser, P. ; Pape, H. ; Lönnig, W.E. ; Saedler, H. ; Schwarz‐Sommer, Z.</creator><creatorcontrib>Sommer, H. ; Beltrán, J.P. ; Huijser, P. ; Pape, H. ; Lönnig, W.E. ; Saedler, H. ; Schwarz‐Sommer, Z.</creatorcontrib><description>Deficiens (defA+) is a homeotic gene involved in the genetic control of Antirrhinum majus flower development. Mutation of this gene (defA‐1) causes homeotic transformation of petals into sepals and of stamina into carpels in flowers displaying the ‘globifera’ phenotype, as shown by cross sections and scanning electronmicroscopy of developing flowers. A cDNA derived from the wild type defA+ gene has been cloned by differential screening of a subtracted ‘flower specific’ cDNA library. The identity of this cDNA with the defA+ gene product has been confirmed by utilizing the somatic and germinal instability of defA‐1 mutants. According to Northern blot analyses the defA+ gene is expressed in flowers but not in leaves, and its expression is nearly constant during all stages of flower development. The 1.1 kb long mRNA has a 681 bp long open reading frame that can code for a putative protein of 227 amino acids (mol. wt 26.2 kd). At its N‐terminus the DEF A protein reveals homology to a conserved domain of the regulatory proteins SRF (activating c‐fos) in mammals and GRM/PRTF (regulating mating type) in yeast. We discuss the structure and the possible function of the DEF A protein in the control of floral organogenesis.</description><identifier>ISSN: 0261-4189</identifier><identifier>EISSN: 1460-2075</identifier><identifier>DOI: 10.1002/j.1460-2075.1990.tb08152.x</identifier><identifier>PMID: 1968830</identifier><identifier>CODEN: EMJODG</identifier><language>eng</language><publisher>London: Nature Publishing Group</publisher><subject>Amino Acid Sequence ; Base Sequence ; Biological and medical sciences ; DEFICIENS Protein ; DNA - genetics ; Fundamental and applied biological sciences. Psychology ; Gene Library ; genes ; Genes, Homeobox ; Genes. Genome ; Homeodomain Proteins - genetics ; Microscopy, Electron, Scanning ; Molecular and cellular biology ; Molecular genetics ; Molecular Sequence Data ; Morphogenesis ; Mutation ; Phosphorylation ; Plant Development ; Plant Proteins - genetics ; Plants - genetics ; Plants - ultrastructure ; Protein Biosynthesis ; Sequence Homology, Nucleic Acid ; transcription factors ; Transcription Factors - genetics</subject><ispartof>The EMBO journal, 1990-03, Vol.9 (3), p.605-613</ispartof><rights>1990 European Molecular Biology Organization</rights><rights>1990 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c6042-98b793ec3a8167255b1cde54d6af32931d2779a6371d9cdbe6a197d26df9e06f3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC551713/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC551713/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=6804178$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1968830$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sommer, H.</creatorcontrib><creatorcontrib>Beltrán, J.P.</creatorcontrib><creatorcontrib>Huijser, P.</creatorcontrib><creatorcontrib>Pape, H.</creatorcontrib><creatorcontrib>Lönnig, W.E.</creatorcontrib><creatorcontrib>Saedler, H.</creatorcontrib><creatorcontrib>Schwarz‐Sommer, Z.</creatorcontrib><title>Deficiens, a homeotic gene involved in the control of flower morphogenesis in Antirrhinum majus: the protein shows homology to transcription factors</title><title>The EMBO journal</title><addtitle>EMBO J</addtitle><description>Deficiens (defA+) is a homeotic gene involved in the genetic control of Antirrhinum majus flower development. Mutation of this gene (defA‐1) causes homeotic transformation of petals into sepals and of stamina into carpels in flowers displaying the ‘globifera’ phenotype, as shown by cross sections and scanning electronmicroscopy of developing flowers. A cDNA derived from the wild type defA+ gene has been cloned by differential screening of a subtracted ‘flower specific’ cDNA library. The identity of this cDNA with the defA+ gene product has been confirmed by utilizing the somatic and germinal instability of defA‐1 mutants. According to Northern blot analyses the defA+ gene is expressed in flowers but not in leaves, and its expression is nearly constant during all stages of flower development. The 1.1 kb long mRNA has a 681 bp long open reading frame that can code for a putative protein of 227 amino acids (mol. wt 26.2 kd). At its N‐terminus the DEF A protein reveals homology to a conserved domain of the regulatory proteins SRF (activating c‐fos) in mammals and GRM/PRTF (regulating mating type) in yeast. We discuss the structure and the possible function of the DEF A protein in the control of floral organogenesis.</description><subject>Amino Acid Sequence</subject><subject>Base Sequence</subject><subject>Biological and medical sciences</subject><subject>DEFICIENS Protein</subject><subject>DNA - genetics</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Gene Library</subject><subject>genes</subject><subject>Genes, Homeobox</subject><subject>Genes. Genome</subject><subject>Homeodomain Proteins - genetics</subject><subject>Microscopy, Electron, Scanning</subject><subject>Molecular and cellular biology</subject><subject>Molecular genetics</subject><subject>Molecular Sequence Data</subject><subject>Morphogenesis</subject><subject>Mutation</subject><subject>Phosphorylation</subject><subject>Plant Development</subject><subject>Plant Proteins - genetics</subject><subject>Plants - genetics</subject><subject>Plants - ultrastructure</subject><subject>Protein Biosynthesis</subject><subject>Sequence Homology, Nucleic Acid</subject><subject>transcription factors</subject><subject>Transcription Factors - genetics</subject><issn>0261-4189</issn><issn>1460-2075</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkcuO0zAUhiMEGjoDj4BkIcSKFjsXX0ZiUYbhpkFsYG05zknjKsnp2E47fY95YJJpVWCFWNnS__32sb8kecnoglGavl0vWM7pPKWiWDCl6CKWVLIiXdw9Sman6HEyoyln85xJ9TQ5D2FNKS2kYGfJGVNcyozOkvsPUDvroA9viCENdoDRWbKCHojrt9huoRo3JDZALPbRY0uwJnWLO_CkQ79pcIKDCxO27KPzvnH90JHOrIdw-dDceIwwxqHBXZhuwRZXexKRRG_6YL3bRIc9qY2N6MOz5Elt2gDPj-tF8vPj9Y-rz_Ob75--XC1v5pbTPJ0rWQqVgc2MZFykRVEyW0GRV9zUWaoyVqVCKMMzwSplqxK4YUpUKa9qBZTX2UXy7nDuZig7qCyM7zOt3njXGb_XaJz-O-ldo1e41UXBBMvG_utj3-PtACHqzgULbWt6wCFooTiXuUr_CbJCqmz0NoKXB9B6DMFDfRqGUT2512s9CdaTYD2510f3-m4sv_jzOb-rB9lj_uqYm2BNW49fb104YVzSnAk5YssDtnMt7P9jAH397f3Xh332CyY00TU</recordid><startdate>199003</startdate><enddate>199003</enddate><creator>Sommer, H.</creator><creator>Beltrán, J.P.</creator><creator>Huijser, P.</creator><creator>Pape, H.</creator><creator>Lönnig, W.E.</creator><creator>Saedler, H.</creator><creator>Schwarz‐Sommer, Z.</creator><general>Nature Publishing Group</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7TM</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>M81</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>199003</creationdate><title>Deficiens, a homeotic gene involved in the control of flower morphogenesis in Antirrhinum majus: the protein shows homology to transcription factors</title><author>Sommer, H. ; Beltrán, J.P. ; Huijser, P. ; Pape, H. ; Lönnig, W.E. ; Saedler, H. ; Schwarz‐Sommer, Z.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c6042-98b793ec3a8167255b1cde54d6af32931d2779a6371d9cdbe6a197d26df9e06f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Amino Acid Sequence</topic><topic>Base Sequence</topic><topic>Biological and medical sciences</topic><topic>DEFICIENS Protein</topic><topic>DNA - genetics</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Gene Library</topic><topic>genes</topic><topic>Genes, Homeobox</topic><topic>Genes. Genome</topic><topic>Homeodomain Proteins - genetics</topic><topic>Microscopy, Electron, Scanning</topic><topic>Molecular and cellular biology</topic><topic>Molecular genetics</topic><topic>Molecular Sequence Data</topic><topic>Morphogenesis</topic><topic>Mutation</topic><topic>Phosphorylation</topic><topic>Plant Development</topic><topic>Plant Proteins - genetics</topic><topic>Plants - genetics</topic><topic>Plants - ultrastructure</topic><topic>Protein Biosynthesis</topic><topic>Sequence Homology, Nucleic Acid</topic><topic>transcription factors</topic><topic>Transcription Factors - genetics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sommer, H.</creatorcontrib><creatorcontrib>Beltrán, J.P.</creatorcontrib><creatorcontrib>Huijser, P.</creatorcontrib><creatorcontrib>Pape, H.</creatorcontrib><creatorcontrib>Lönnig, W.E.</creatorcontrib><creatorcontrib>Saedler, H.</creatorcontrib><creatorcontrib>Schwarz‐Sommer, Z.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Nucleic Acids Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biochemistry Abstracts 3</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The EMBO journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sommer, H.</au><au>Beltrán, J.P.</au><au>Huijser, P.</au><au>Pape, H.</au><au>Lönnig, W.E.</au><au>Saedler, H.</au><au>Schwarz‐Sommer, Z.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Deficiens, a homeotic gene involved in the control of flower morphogenesis in Antirrhinum majus: the protein shows homology to transcription factors</atitle><jtitle>The EMBO journal</jtitle><addtitle>EMBO J</addtitle><date>1990-03</date><risdate>1990</risdate><volume>9</volume><issue>3</issue><spage>605</spage><epage>613</epage><pages>605-613</pages><issn>0261-4189</issn><eissn>1460-2075</eissn><coden>EMJODG</coden><abstract>Deficiens (defA+) is a homeotic gene involved in the genetic control of Antirrhinum majus flower development. Mutation of this gene (defA‐1) causes homeotic transformation of petals into sepals and of stamina into carpels in flowers displaying the ‘globifera’ phenotype, as shown by cross sections and scanning electronmicroscopy of developing flowers. A cDNA derived from the wild type defA+ gene has been cloned by differential screening of a subtracted ‘flower specific’ cDNA library. The identity of this cDNA with the defA+ gene product has been confirmed by utilizing the somatic and germinal instability of defA‐1 mutants. According to Northern blot analyses the defA+ gene is expressed in flowers but not in leaves, and its expression is nearly constant during all stages of flower development. The 1.1 kb long mRNA has a 681 bp long open reading frame that can code for a putative protein of 227 amino acids (mol. wt 26.2 kd). At its N‐terminus the DEF A protein reveals homology to a conserved domain of the regulatory proteins SRF (activating c‐fos) in mammals and GRM/PRTF (regulating mating type) in yeast. We discuss the structure and the possible function of the DEF A protein in the control of floral organogenesis.</abstract><cop>London</cop><pub>Nature Publishing Group</pub><pmid>1968830</pmid><doi>10.1002/j.1460-2075.1990.tb08152.x</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0261-4189 |
| ispartof | The EMBO journal, 1990-03, Vol.9 (3), p.605-613 |
| issn | 0261-4189 1460-2075 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_551713 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection; Free Full-Text Journals in Chemistry |
| subjects | Amino Acid Sequence Base Sequence Biological and medical sciences DEFICIENS Protein DNA - genetics Fundamental and applied biological sciences. Psychology Gene Library genes Genes, Homeobox Genes. Genome Homeodomain Proteins - genetics Microscopy, Electron, Scanning Molecular and cellular biology Molecular genetics Molecular Sequence Data Morphogenesis Mutation Phosphorylation Plant Development Plant Proteins - genetics Plants - genetics Plants - ultrastructure Protein Biosynthesis Sequence Homology, Nucleic Acid transcription factors Transcription Factors - genetics |
| title | Deficiens, a homeotic gene involved in the control of flower morphogenesis in Antirrhinum majus: the protein shows homology to transcription factors |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-10T19%3A42%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Deficiens,%20a%20homeotic%20gene%20involved%20in%20the%20control%20of%20flower%20morphogenesis%20in%20Antirrhinum%20majus:%20the%20protein%20shows%20homology%20to%20transcription%20factors&rft.jtitle=The%20EMBO%20journal&rft.au=Sommer,%20H.&rft.date=1990-03&rft.volume=9&rft.issue=3&rft.spage=605&rft.epage=613&rft.pages=605-613&rft.issn=0261-4189&rft.eissn=1460-2075&rft.coden=EMJODG&rft_id=info:doi/10.1002/j.1460-2075.1990.tb08152.x&rft_dat=%3Cproquest_pubme%3E79668492%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=15893460&rft_id=info:pmid/1968830&rfr_iscdi=true |