Region-specific aging of the human brain as evidenced by neurochemical profiles measured noninvasively in the posterior cingulate cortex and the occipital lobe using 1H magnetic resonance spectroscopy at 7 T

[Display omitted] •Age-associated neurochemical concentration differences were measured non-invasively.•Differences in 8 out of 14 neurochemicals were observed.•Several differences reflect known region-specific differences in blood flow, metabolism and connectivity.•Others reveal new aspects of neur...

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Veröffentlicht in:Neuroscience 2017-06, Vol.354, p.168-177
Hauptverfasser: Marjańska, Małgorzata, McCarten, J. Riley, Hodges, James, Hemmy, Laura S., Grant, Andrea, Deelchand, Dinesh K., Terpstra, Melissa
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Sprache:eng
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