Men and Women Demonstrate Differences in Early Functional Recovery After Total Knee Arthroplasty
Abstract Objective To investigate whether sex affects the trajectory of functional recovery after total knee arthroplasty (TKA). Design Retrospective analysis from a historical database containing data from 3 prospective clinical trials and a pilot study. Setting Clinical laboratory setting. Partici...
Gespeichert in:
| Veröffentlicht in: | Archives of physical medicine and rehabilitation 2016-07, Vol.97 (7), p.1154-1162 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1162 |
|---|---|
| container_issue | 7 |
| container_start_page | 1154 |
| container_title | Archives of physical medicine and rehabilitation |
| container_volume | 97 |
| creator | Gustavson, Allison M., PT, DPT Wolfe, Pamela, MS Falvey, Jason R., PT, DPT Eckhoff, Donald G., MD Toth, Michael J., PhD Stevens-Lapsley, Jennifer E., PT, PhD |
| description | Abstract Objective To investigate whether sex affects the trajectory of functional recovery after total knee arthroplasty (TKA). Design Retrospective analysis from a historical database containing data from 3 prospective clinical trials and a pilot study. Setting Clinical laboratory setting. Participants Recruitment across studies was restricted to patients who underwent an elective unilateral TKA for the treatment of osteoarthritis and were between 50 and 85 years of age (N=301). Interventions Across all 4 studies, patients received a TKA and physical therapy intervention. Measures of physical function and strength were assessed before TKA and 1, 3, and 6 months after TKA. Main Outcome Measures Using a repeated-measures maximum likelihood model, statistical inference was made to estimate the changes in outcomes from before surgery to 1, 3, and 6 months after TKA that were stratified by sex. Muscle strength was assessed during maximal isometric quadriceps and hamstrings contractions. Muscle activation was assessed in the quadriceps muscle. Physical function outcomes included timed Up and Go (TUG) test, stair climbing test, and 6-minute walk test (6MWT). Results Women demonstrated less decline in quadriceps strength than did men at 1, 3, and 6 months after TKA ( P |
| doi_str_mv | 10.1016/j.apmr.2016.03.007 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5513149</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0003999316300429</els_id><sourcerecordid>1957114887</sourcerecordid><originalsourceid>FETCH-LOGICAL-c543t-df0caee9905d13ddf49931124b9dc4637be97d36594276824d0fc9481ef57a333</originalsourceid><addsrcrecordid>eNqFkk1v1DAQhiMEokvhD3BAOXJJ6o84jiVUadUPqChCgiK4Ga89oV4Se7GdlfLvcbSlAg5w8nj8zqsZP1MUzzGqMcLtybZWuzHUJMc1ojVC_EGxwoySqiP4y8NihRCilRCCHhVPYtzma8soflwcEY5aSlu6Kr6-A1cqZ8rPfszROYzexRRUgvLc9j0EcBpiaV15ocIwl5eT08l6p4byA2i_hzCX6z5BKG98ysm3DqBch3Qb_G5QMc1Pi0e9GiI8uzuPi0-XFzdnb6rr96-vztbXlWYNTZXpkVYAQiBmMDWmb3LbGJNmI4xuWso3ILihLRMN4W1HGoN6LZoOQ8-4opQeF6cH3920GcFocHmKQe6CHVWYpVdW_vni7K385veSMUxxI7LByzuD4H9MEJMcbdQwDMqBn6LEgnGMm67j_5dyIRjjHJMsJQepDj7GAP19RxjJhaLcyoWiXChKRGWmmIte_D7LfckvbFnw6iCA_KN7C0FGbRdSxgbQSRpv_-1_-le5HqyzWg3fYYa49VPIgPMcMhKJ5Mdlj5Y1wi1FqCGC_gToeMPn</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1799557712</pqid></control><display><type>article</type><title>Men and Women Demonstrate Differences in Early Functional Recovery After Total Knee Arthroplasty</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Gustavson, Allison M., PT, DPT ; Wolfe, Pamela, MS ; Falvey, Jason R., PT, DPT ; Eckhoff, Donald G., MD ; Toth, Michael J., PhD ; Stevens-Lapsley, Jennifer E., PT, PhD</creator><creatorcontrib>Gustavson, Allison M., PT, DPT ; Wolfe, Pamela, MS ; Falvey, Jason R., PT, DPT ; Eckhoff, Donald G., MD ; Toth, Michael J., PhD ; Stevens-Lapsley, Jennifer E., PT, PhD</creatorcontrib><description>Abstract Objective To investigate whether sex affects the trajectory of functional recovery after total knee arthroplasty (TKA). Design Retrospective analysis from a historical database containing data from 3 prospective clinical trials and a pilot study. Setting Clinical laboratory setting. Participants Recruitment across studies was restricted to patients who underwent an elective unilateral TKA for the treatment of osteoarthritis and were between 50 and 85 years of age (N=301). Interventions Across all 4 studies, patients received a TKA and physical therapy intervention. Measures of physical function and strength were assessed before TKA and 1, 3, and 6 months after TKA. Main Outcome Measures Using a repeated-measures maximum likelihood model, statistical inference was made to estimate the changes in outcomes from before surgery to 1, 3, and 6 months after TKA that were stratified by sex. Muscle strength was assessed during maximal isometric quadriceps and hamstrings contractions. Muscle activation was assessed in the quadriceps muscle. Physical function outcomes included timed Up and Go (TUG) test, stair climbing test, and 6-minute walk test (6MWT). Results Women demonstrated less decline in quadriceps strength than did men at 1, 3, and 6 months after TKA ( P <.04), whereas women demonstrated less decline in hamstrings strength 1 month after TKA ( P <.0001). Women demonstrated a greater decline than did men on the TUG test ( P =.001), stair climbing test ( P =.004), and 6MWT ( P =.001) 1 month after TKA. Sex differences in physical function did not persist at 3 and 6 months after TKA. Conclusions Sex affected early recovery of muscle and physical function in the first month after TKA. Women demonstrated better preservation of quadriceps strength but a greater decline on measures of physical function than did men.</description><identifier>ISSN: 0003-9993</identifier><identifier>EISSN: 1532-821X</identifier><identifier>DOI: 10.1016/j.apmr.2016.03.007</identifier><identifier>PMID: 27063363</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Aged ; Aged, 80 and over ; Arthroplasty, Replacement, Knee - rehabilitation ; Clinical Trials as Topic ; Disability Evaluation ; Female ; Humans ; Isometric Contraction - physiology ; Likelihood Functions ; Male ; Middle Aged ; Mobility Limitation ; Muscle strength ; Muscle, Skeletal - physiopathology ; Physical Medicine and Rehabilitation ; Physical Therapy Modalities ; Quadriceps Muscle - physiopathology ; Recovery of Function ; Rehabilitation ; Retrospective Studies ; Sex Factors ; Time Factors</subject><ispartof>Archives of physical medicine and rehabilitation, 2016-07, Vol.97 (7), p.1154-1162</ispartof><rights>2016</rights><rights>Published by Elsevier Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c543t-df0caee9905d13ddf49931124b9dc4637be97d36594276824d0fc9481ef57a333</citedby><cites>FETCH-LOGICAL-c543t-df0caee9905d13ddf49931124b9dc4637be97d36594276824d0fc9481ef57a333</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0003999316300429$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27063363$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gustavson, Allison M., PT, DPT</creatorcontrib><creatorcontrib>Wolfe, Pamela, MS</creatorcontrib><creatorcontrib>Falvey, Jason R., PT, DPT</creatorcontrib><creatorcontrib>Eckhoff, Donald G., MD</creatorcontrib><creatorcontrib>Toth, Michael J., PhD</creatorcontrib><creatorcontrib>Stevens-Lapsley, Jennifer E., PT, PhD</creatorcontrib><title>Men and Women Demonstrate Differences in Early Functional Recovery After Total Knee Arthroplasty</title><title>Archives of physical medicine and rehabilitation</title><addtitle>Arch Phys Med Rehabil</addtitle><description>Abstract Objective To investigate whether sex affects the trajectory of functional recovery after total knee arthroplasty (TKA). Design Retrospective analysis from a historical database containing data from 3 prospective clinical trials and a pilot study. Setting Clinical laboratory setting. Participants Recruitment across studies was restricted to patients who underwent an elective unilateral TKA for the treatment of osteoarthritis and were between 50 and 85 years of age (N=301). Interventions Across all 4 studies, patients received a TKA and physical therapy intervention. Measures of physical function and strength were assessed before TKA and 1, 3, and 6 months after TKA. Main Outcome Measures Using a repeated-measures maximum likelihood model, statistical inference was made to estimate the changes in outcomes from before surgery to 1, 3, and 6 months after TKA that were stratified by sex. Muscle strength was assessed during maximal isometric quadriceps and hamstrings contractions. Muscle activation was assessed in the quadriceps muscle. Physical function outcomes included timed Up and Go (TUG) test, stair climbing test, and 6-minute walk test (6MWT). Results Women demonstrated less decline in quadriceps strength than did men at 1, 3, and 6 months after TKA ( P <.04), whereas women demonstrated less decline in hamstrings strength 1 month after TKA ( P <.0001). Women demonstrated a greater decline than did men on the TUG test ( P =.001), stair climbing test ( P =.004), and 6MWT ( P =.001) 1 month after TKA. Sex differences in physical function did not persist at 3 and 6 months after TKA. Conclusions Sex affected early recovery of muscle and physical function in the first month after TKA. Women demonstrated better preservation of quadriceps strength but a greater decline on measures of physical function than did men.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Arthroplasty, Replacement, Knee - rehabilitation</subject><subject>Clinical Trials as Topic</subject><subject>Disability Evaluation</subject><subject>Female</subject><subject>Humans</subject><subject>Isometric Contraction - physiology</subject><subject>Likelihood Functions</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mobility Limitation</subject><subject>Muscle strength</subject><subject>Muscle, Skeletal - physiopathology</subject><subject>Physical Medicine and Rehabilitation</subject><subject>Physical Therapy Modalities</subject><subject>Quadriceps Muscle - physiopathology</subject><subject>Recovery of Function</subject><subject>Rehabilitation</subject><subject>Retrospective Studies</subject><subject>Sex Factors</subject><subject>Time Factors</subject><issn>0003-9993</issn><issn>1532-821X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkk1v1DAQhiMEokvhD3BAOXJJ6o84jiVUadUPqChCgiK4Ga89oV4Se7GdlfLvcbSlAg5w8nj8zqsZP1MUzzGqMcLtybZWuzHUJMc1ojVC_EGxwoySqiP4y8NihRCilRCCHhVPYtzma8soflwcEY5aSlu6Kr6-A1cqZ8rPfszROYzexRRUgvLc9j0EcBpiaV15ocIwl5eT08l6p4byA2i_hzCX6z5BKG98ysm3DqBch3Qb_G5QMc1Pi0e9GiI8uzuPi0-XFzdnb6rr96-vztbXlWYNTZXpkVYAQiBmMDWmb3LbGJNmI4xuWso3ILihLRMN4W1HGoN6LZoOQ8-4opQeF6cH3920GcFocHmKQe6CHVWYpVdW_vni7K385veSMUxxI7LByzuD4H9MEJMcbdQwDMqBn6LEgnGMm67j_5dyIRjjHJMsJQepDj7GAP19RxjJhaLcyoWiXChKRGWmmIte_D7LfckvbFnw6iCA_KN7C0FGbRdSxgbQSRpv_-1_-le5HqyzWg3fYYa49VPIgPMcMhKJ5Mdlj5Y1wi1FqCGC_gToeMPn</recordid><startdate>20160701</startdate><enddate>20160701</enddate><creator>Gustavson, Allison M., PT, DPT</creator><creator>Wolfe, Pamela, MS</creator><creator>Falvey, Jason R., PT, DPT</creator><creator>Eckhoff, Donald G., MD</creator><creator>Toth, Michael J., PhD</creator><creator>Stevens-Lapsley, Jennifer E., PT, PhD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20160701</creationdate><title>Men and Women Demonstrate Differences in Early Functional Recovery After Total Knee Arthroplasty</title><author>Gustavson, Allison M., PT, DPT ; Wolfe, Pamela, MS ; Falvey, Jason R., PT, DPT ; Eckhoff, Donald G., MD ; Toth, Michael J., PhD ; Stevens-Lapsley, Jennifer E., PT, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c543t-df0caee9905d13ddf49931124b9dc4637be97d36594276824d0fc9481ef57a333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Arthroplasty, Replacement, Knee - rehabilitation</topic><topic>Clinical Trials as Topic</topic><topic>Disability Evaluation</topic><topic>Female</topic><topic>Humans</topic><topic>Isometric Contraction - physiology</topic><topic>Likelihood Functions</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mobility Limitation</topic><topic>Muscle strength</topic><topic>Muscle, Skeletal - physiopathology</topic><topic>Physical Medicine and Rehabilitation</topic><topic>Physical Therapy Modalities</topic><topic>Quadriceps Muscle - physiopathology</topic><topic>Recovery of Function</topic><topic>Rehabilitation</topic><topic>Retrospective Studies</topic><topic>Sex Factors</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gustavson, Allison M., PT, DPT</creatorcontrib><creatorcontrib>Wolfe, Pamela, MS</creatorcontrib><creatorcontrib>Falvey, Jason R., PT, DPT</creatorcontrib><creatorcontrib>Eckhoff, Donald G., MD</creatorcontrib><creatorcontrib>Toth, Michael J., PhD</creatorcontrib><creatorcontrib>Stevens-Lapsley, Jennifer E., PT, PhD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Archives of physical medicine and rehabilitation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gustavson, Allison M., PT, DPT</au><au>Wolfe, Pamela, MS</au><au>Falvey, Jason R., PT, DPT</au><au>Eckhoff, Donald G., MD</au><au>Toth, Michael J., PhD</au><au>Stevens-Lapsley, Jennifer E., PT, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Men and Women Demonstrate Differences in Early Functional Recovery After Total Knee Arthroplasty</atitle><jtitle>Archives of physical medicine and rehabilitation</jtitle><addtitle>Arch Phys Med Rehabil</addtitle><date>2016-07-01</date><risdate>2016</risdate><volume>97</volume><issue>7</issue><spage>1154</spage><epage>1162</epage><pages>1154-1162</pages><issn>0003-9993</issn><eissn>1532-821X</eissn><abstract>Abstract Objective To investigate whether sex affects the trajectory of functional recovery after total knee arthroplasty (TKA). Design Retrospective analysis from a historical database containing data from 3 prospective clinical trials and a pilot study. Setting Clinical laboratory setting. Participants Recruitment across studies was restricted to patients who underwent an elective unilateral TKA for the treatment of osteoarthritis and were between 50 and 85 years of age (N=301). Interventions Across all 4 studies, patients received a TKA and physical therapy intervention. Measures of physical function and strength were assessed before TKA and 1, 3, and 6 months after TKA. Main Outcome Measures Using a repeated-measures maximum likelihood model, statistical inference was made to estimate the changes in outcomes from before surgery to 1, 3, and 6 months after TKA that were stratified by sex. Muscle strength was assessed during maximal isometric quadriceps and hamstrings contractions. Muscle activation was assessed in the quadriceps muscle. Physical function outcomes included timed Up and Go (TUG) test, stair climbing test, and 6-minute walk test (6MWT). Results Women demonstrated less decline in quadriceps strength than did men at 1, 3, and 6 months after TKA ( P <.04), whereas women demonstrated less decline in hamstrings strength 1 month after TKA ( P <.0001). Women demonstrated a greater decline than did men on the TUG test ( P =.001), stair climbing test ( P =.004), and 6MWT ( P =.001) 1 month after TKA. Sex differences in physical function did not persist at 3 and 6 months after TKA. Conclusions Sex affected early recovery of muscle and physical function in the first month after TKA. Women demonstrated better preservation of quadriceps strength but a greater decline on measures of physical function than did men.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>27063363</pmid><doi>10.1016/j.apmr.2016.03.007</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0003-9993 |
| ispartof | Archives of physical medicine and rehabilitation, 2016-07, Vol.97 (7), p.1154-1162 |
| issn | 0003-9993 1532-821X |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5513149 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Aged Aged, 80 and over Arthroplasty, Replacement, Knee - rehabilitation Clinical Trials as Topic Disability Evaluation Female Humans Isometric Contraction - physiology Likelihood Functions Male Middle Aged Mobility Limitation Muscle strength Muscle, Skeletal - physiopathology Physical Medicine and Rehabilitation Physical Therapy Modalities Quadriceps Muscle - physiopathology Recovery of Function Rehabilitation Retrospective Studies Sex Factors Time Factors |
| title | Men and Women Demonstrate Differences in Early Functional Recovery After Total Knee Arthroplasty |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-14T19%3A47%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Men%20and%20Women%20Demonstrate%20Differences%20in%20Early%20Functional%20Recovery%20After%20Total%20Knee%20Arthroplasty&rft.jtitle=Archives%20of%20physical%20medicine%20and%20rehabilitation&rft.au=Gustavson,%20Allison%20M.,%20PT,%20DPT&rft.date=2016-07-01&rft.volume=97&rft.issue=7&rft.spage=1154&rft.epage=1162&rft.pages=1154-1162&rft.issn=0003-9993&rft.eissn=1532-821X&rft_id=info:doi/10.1016/j.apmr.2016.03.007&rft_dat=%3Cproquest_pubme%3E1957114887%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1799557712&rft_id=info:pmid/27063363&rft_els_id=1_s2_0_S0003999316300429&rfr_iscdi=true |