Ultrasoft microwire neural electrodes improve chronic tissue integration

[Display omitted] Chronically implanted neural multi-electrode arrays (MEA) are an essential technology for recording electrical signals from neurons and/or modulating neural activity through stimulation. However, current MEAs, regardless of the type, elicit an inflammatory response that ultimately...

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Veröffentlicht in:	Acta biomaterialia 2017-04, Vol.53, p.46-58
Hauptverfasser:	Du, Zhanhong Jeff, Kolarcik, Christi L., Kozai, Takashi D.Y., Luebben, Silvia D., Sapp, Shawn A., Zheng, Xin Sally, Nabity, James A., Cui, X. Tracy
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biocompatible Materials - adverse effects Biocompatible Materials - chemistry Blood-Brain Barrier Composite bio-electrodes Conducting elastomer Deep brain stimulation Electric Conductivity Electric Stimulation Electrodes, Implanted - adverse effects Foreign-Body Reaction - prevention & control Inflammation - prevention & control Male Materials Testing Microelectrodes - adverse effects Neural electrode Neurons - physiology Polymers Rats Rats, Sprague-Dawley Silicone Elastomers Subthalamic Nucleus - physiology Subthalamic Nucleus - surgery Tungsten - adverse effects
Online-Zugang:	Volltext
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