Factors affecting revision rate of chronic rhinosinusitis
Objective Chronic rhinosinusitis (CRS) is a variable multifactorial disease. It can be divided into forms with nasal polyps (CRSwNP) and without (CRSsNP). Sinus and/or nasal polypectomy surgery are considered if maximal conservative treatment is insufficient. The predictive factors of the need of re...
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| Veröffentlicht in: | Laryngoscope investigative otolaryngology 2016-08, Vol.1 (4), p.96-105 |
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| creator | Koskinen, Anni Salo, Riikka Huhtala, Heini Myller, Jyri Rautiainen, Markus Kääriäinen, Janne Penttilä, Matti Renkonen, Risto Raitiola, Hannu Mäkelä, Mika Toppila‐Salmi, Sanna |
| description | Objective
Chronic rhinosinusitis (CRS) is a variable multifactorial disease. It can be divided into forms with nasal polyps (CRSwNP) and without (CRSsNP). Sinus and/or nasal polypectomy surgery are considered if maximal conservative treatment is insufficient. The predictive factors of the need of revision surgery comprise mostly the CRSwNP phenotype and are not fully understood.
Study Design
The aim of this follow‐up study was to evaluate the factors associated with the revision surgery rate in CRS patients with variable extent of disease.
Methods
Data of CRS patients (N = 178) undergoing sinus surgery and/or nasal polypectomy in 2001 to 2010 were used. Patient characteristics and follow‐up data were collected from patient records and questionnaires. Associations were analyzed by Fisher's exact, Mann Whitney U, and the Kaplan‐Meier method with log‐rank test. Unadjusted Cox's proportional hazard models were used for 12 variables and were fitted for the need for revision sinus surgery and/or nasal polypectomy during follow‐up of in average 9 years.
Results
The proportion of CRS patients who had undergone revision in 5 years was 9.6%. After adjustment, the following factors associated significantly with the need for recurrent CRS surgery: allergic rhinitis, corticosteroid treatment, previous surgery of CRS, and recurrent NP.
Conclusion
Increased risk of progressive CRS phenotypes with the need for revision surgery would putatively be recognized by relatively simple clinical questions. Further studies with increased sample size are needed to evaluate whether these predictive factors would be relevant for developing better detection and management of progressive CRS.
Level of Evidence
2b. |
| doi_str_mv | 10.1002/lio2.27 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5510254</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2290756531</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4337-84473aa61481b43276a60f3580040756f0c68acfde0093ab46db8869b39561263</originalsourceid><addsrcrecordid>eNp1kV1LwzAUhoMoOubwH0jBCwXZPPlomt4IMpwOBrvR65Bm6Rbpkpm0k_17OzbHFLw6gfPw5E1ehK4wDDAAeaisJwOSnaAOoZnoC6Di9Oh8gXoxfgAA5oRzAefoggiRMwFZB-UjpWsfYqLK0ujaunkSzNpG610SVG0SXyZ6EbyzOgkL63y0rom2tvESnZWqiqa3n130Pnp-G772J9OX8fBp0teM0qwvGMuoUhwzgQtGScYVh5KmAoBBlvISNBdKlzMDkFNVMD4rhOB5QfOUY8JpFz3uvKumWJqZNq4OqpKrYJcqbKRXVv7eOLuQc7-WaYqBpKwV3O0FwX82JtZyaaM2VaWc8U2UOKcC56K9r0Vv_qAfvgmufZ4kJN_GTSluqdsdpYOPMZjyEAaD3DYit41IkrXk9XH2A_fz_y1wvwO-bGU2_3nkZDwlre4bpSOSyQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2290756531</pqid></control><display><type>article</type><title>Factors affecting revision rate of chronic rhinosinusitis</title><source>Wiley Online Library Open Access</source><source>DOAJ Directory of Open Access Journals</source><source>Wiley Online Library Journals Frontfile Complete</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Koskinen, Anni ; Salo, Riikka ; Huhtala, Heini ; Myller, Jyri ; Rautiainen, Markus ; Kääriäinen, Janne ; Penttilä, Matti ; Renkonen, Risto ; Raitiola, Hannu ; Mäkelä, Mika ; Toppila‐Salmi, Sanna</creator><creatorcontrib>Koskinen, Anni ; Salo, Riikka ; Huhtala, Heini ; Myller, Jyri ; Rautiainen, Markus ; Kääriäinen, Janne ; Penttilä, Matti ; Renkonen, Risto ; Raitiola, Hannu ; Mäkelä, Mika ; Toppila‐Salmi, Sanna</creatorcontrib><description>Objective
Chronic rhinosinusitis (CRS) is a variable multifactorial disease. It can be divided into forms with nasal polyps (CRSwNP) and without (CRSsNP). Sinus and/or nasal polypectomy surgery are considered if maximal conservative treatment is insufficient. The predictive factors of the need of revision surgery comprise mostly the CRSwNP phenotype and are not fully understood.
Study Design
The aim of this follow‐up study was to evaluate the factors associated with the revision surgery rate in CRS patients with variable extent of disease.
Methods
Data of CRS patients (N = 178) undergoing sinus surgery and/or nasal polypectomy in 2001 to 2010 were used. Patient characteristics and follow‐up data were collected from patient records and questionnaires. Associations were analyzed by Fisher's exact, Mann Whitney U, and the Kaplan‐Meier method with log‐rank test. Unadjusted Cox's proportional hazard models were used for 12 variables and were fitted for the need for revision sinus surgery and/or nasal polypectomy during follow‐up of in average 9 years.
Results
The proportion of CRS patients who had undergone revision in 5 years was 9.6%. After adjustment, the following factors associated significantly with the need for recurrent CRS surgery: allergic rhinitis, corticosteroid treatment, previous surgery of CRS, and recurrent NP.
Conclusion
Increased risk of progressive CRS phenotypes with the need for revision surgery would putatively be recognized by relatively simple clinical questions. Further studies with increased sample size are needed to evaluate whether these predictive factors would be relevant for developing better detection and management of progressive CRS.
Level of Evidence
2b.</description><identifier>ISSN: 2378-8038</identifier><identifier>ISSN: 0023-852X</identifier><identifier>EISSN: 2378-8038</identifier><identifier>DOI: 10.1002/lio2.27</identifier><identifier>PMID: 28894807</identifier><language>eng</language><publisher>United States: John Wiley & Sons, Inc</publisher><subject>Allergy, Rhinology, and Immunology ; Antrochoanal polyp ; aspirin intolerance ; aspirin‐exacerbated respiratory disease ; Asthma ; Chronic illnesses ; Clinical trials ; Cystic fibrosis ; Endoscopy ; Genotype & phenotype ; Hospitals ; inflammation ; nasal polyp ; Nose ; Otolaryngology ; Patients ; Polyps ; Population ; recurrence ; revision surgery ; Rhinitis ; sinus surgery ; Sinuses ; Sinusitis ; Studies ; Surgery</subject><ispartof>Laryngoscope investigative otolaryngology, 2016-08, Vol.1 (4), p.96-105</ispartof><rights>2016 The Authors Laryngoscope Investigative Otolaryngology published by Wiley Periodicals, Inc. on behalf of The Triological Society</rights><rights>2016. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4337-84473aa61481b43276a60f3580040756f0c68acfde0093ab46db8869b39561263</citedby><cites>FETCH-LOGICAL-c4337-84473aa61481b43276a60f3580040756f0c68acfde0093ab46db8869b39561263</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510254/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510254/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,1411,11541,27901,27902,45550,45551,46027,46451,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28894807$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Koskinen, Anni</creatorcontrib><creatorcontrib>Salo, Riikka</creatorcontrib><creatorcontrib>Huhtala, Heini</creatorcontrib><creatorcontrib>Myller, Jyri</creatorcontrib><creatorcontrib>Rautiainen, Markus</creatorcontrib><creatorcontrib>Kääriäinen, Janne</creatorcontrib><creatorcontrib>Penttilä, Matti</creatorcontrib><creatorcontrib>Renkonen, Risto</creatorcontrib><creatorcontrib>Raitiola, Hannu</creatorcontrib><creatorcontrib>Mäkelä, Mika</creatorcontrib><creatorcontrib>Toppila‐Salmi, Sanna</creatorcontrib><title>Factors affecting revision rate of chronic rhinosinusitis</title><title>Laryngoscope investigative otolaryngology</title><addtitle>Laryngoscope Investig Otolaryngol</addtitle><description>Objective
Chronic rhinosinusitis (CRS) is a variable multifactorial disease. It can be divided into forms with nasal polyps (CRSwNP) and without (CRSsNP). Sinus and/or nasal polypectomy surgery are considered if maximal conservative treatment is insufficient. The predictive factors of the need of revision surgery comprise mostly the CRSwNP phenotype and are not fully understood.
Study Design
The aim of this follow‐up study was to evaluate the factors associated with the revision surgery rate in CRS patients with variable extent of disease.
Methods
Data of CRS patients (N = 178) undergoing sinus surgery and/or nasal polypectomy in 2001 to 2010 were used. Patient characteristics and follow‐up data were collected from patient records and questionnaires. Associations were analyzed by Fisher's exact, Mann Whitney U, and the Kaplan‐Meier method with log‐rank test. Unadjusted Cox's proportional hazard models were used for 12 variables and were fitted for the need for revision sinus surgery and/or nasal polypectomy during follow‐up of in average 9 years.
Results
The proportion of CRS patients who had undergone revision in 5 years was 9.6%. After adjustment, the following factors associated significantly with the need for recurrent CRS surgery: allergic rhinitis, corticosteroid treatment, previous surgery of CRS, and recurrent NP.
Conclusion
Increased risk of progressive CRS phenotypes with the need for revision surgery would putatively be recognized by relatively simple clinical questions. Further studies with increased sample size are needed to evaluate whether these predictive factors would be relevant for developing better detection and management of progressive CRS.
Level of Evidence
2b.</description><subject>Allergy, Rhinology, and Immunology</subject><subject>Antrochoanal polyp</subject><subject>aspirin intolerance</subject><subject>aspirin‐exacerbated respiratory disease</subject><subject>Asthma</subject><subject>Chronic illnesses</subject><subject>Clinical trials</subject><subject>Cystic fibrosis</subject><subject>Endoscopy</subject><subject>Genotype & phenotype</subject><subject>Hospitals</subject><subject>inflammation</subject><subject>nasal polyp</subject><subject>Nose</subject><subject>Otolaryngology</subject><subject>Patients</subject><subject>Polyps</subject><subject>Population</subject><subject>recurrence</subject><subject>revision surgery</subject><subject>Rhinitis</subject><subject>sinus surgery</subject><subject>Sinuses</subject><subject>Sinusitis</subject><subject>Studies</subject><subject>Surgery</subject><issn>2378-8038</issn><issn>0023-852X</issn><issn>2378-8038</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kV1LwzAUhoMoOubwH0jBCwXZPPlomt4IMpwOBrvR65Bm6Rbpkpm0k_17OzbHFLw6gfPw5E1ehK4wDDAAeaisJwOSnaAOoZnoC6Di9Oh8gXoxfgAA5oRzAefoggiRMwFZB-UjpWsfYqLK0ujaunkSzNpG610SVG0SXyZ6EbyzOgkL63y0rom2tvESnZWqiqa3n130Pnp-G772J9OX8fBp0teM0qwvGMuoUhwzgQtGScYVh5KmAoBBlvISNBdKlzMDkFNVMD4rhOB5QfOUY8JpFz3uvKumWJqZNq4OqpKrYJcqbKRXVv7eOLuQc7-WaYqBpKwV3O0FwX82JtZyaaM2VaWc8U2UOKcC56K9r0Vv_qAfvgmufZ4kJN_GTSluqdsdpYOPMZjyEAaD3DYit41IkrXk9XH2A_fz_y1wvwO-bGU2_3nkZDwlre4bpSOSyQ</recordid><startdate>201608</startdate><enddate>201608</enddate><creator>Koskinen, Anni</creator><creator>Salo, Riikka</creator><creator>Huhtala, Heini</creator><creator>Myller, Jyri</creator><creator>Rautiainen, Markus</creator><creator>Kääriäinen, Janne</creator><creator>Penttilä, Matti</creator><creator>Renkonen, Risto</creator><creator>Raitiola, Hannu</creator><creator>Mäkelä, Mika</creator><creator>Toppila‐Salmi, Sanna</creator><general>John Wiley & Sons, Inc</general><general>John Wiley and Sons Inc</general><scope>24P</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>8BM</scope><scope>5PM</scope></search><sort><creationdate>201608</creationdate><title>Factors affecting revision rate of chronic rhinosinusitis</title><author>Koskinen, Anni ; Salo, Riikka ; Huhtala, Heini ; Myller, Jyri ; Rautiainen, Markus ; Kääriäinen, Janne ; Penttilä, Matti ; Renkonen, Risto ; Raitiola, Hannu ; Mäkelä, Mika ; Toppila‐Salmi, Sanna</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4337-84473aa61481b43276a60f3580040756f0c68acfde0093ab46db8869b39561263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Allergy, Rhinology, and Immunology</topic><topic>Antrochoanal polyp</topic><topic>aspirin intolerance</topic><topic>aspirin‐exacerbated respiratory disease</topic><topic>Asthma</topic><topic>Chronic illnesses</topic><topic>Clinical trials</topic><topic>Cystic fibrosis</topic><topic>Endoscopy</topic><topic>Genotype & phenotype</topic><topic>Hospitals</topic><topic>inflammation</topic><topic>nasal polyp</topic><topic>Nose</topic><topic>Otolaryngology</topic><topic>Patients</topic><topic>Polyps</topic><topic>Population</topic><topic>recurrence</topic><topic>revision surgery</topic><topic>Rhinitis</topic><topic>sinus surgery</topic><topic>Sinuses</topic><topic>Sinusitis</topic><topic>Studies</topic><topic>Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Koskinen, Anni</creatorcontrib><creatorcontrib>Salo, Riikka</creatorcontrib><creatorcontrib>Huhtala, Heini</creatorcontrib><creatorcontrib>Myller, Jyri</creatorcontrib><creatorcontrib>Rautiainen, Markus</creatorcontrib><creatorcontrib>Kääriäinen, Janne</creatorcontrib><creatorcontrib>Penttilä, Matti</creatorcontrib><creatorcontrib>Renkonen, Risto</creatorcontrib><creatorcontrib>Raitiola, Hannu</creatorcontrib><creatorcontrib>Mäkelä, Mika</creatorcontrib><creatorcontrib>Toppila‐Salmi, Sanna</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>ComDisDome</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Laryngoscope investigative otolaryngology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Koskinen, Anni</au><au>Salo, Riikka</au><au>Huhtala, Heini</au><au>Myller, Jyri</au><au>Rautiainen, Markus</au><au>Kääriäinen, Janne</au><au>Penttilä, Matti</au><au>Renkonen, Risto</au><au>Raitiola, Hannu</au><au>Mäkelä, Mika</au><au>Toppila‐Salmi, Sanna</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Factors affecting revision rate of chronic rhinosinusitis</atitle><jtitle>Laryngoscope investigative otolaryngology</jtitle><addtitle>Laryngoscope Investig Otolaryngol</addtitle><date>2016-08</date><risdate>2016</risdate><volume>1</volume><issue>4</issue><spage>96</spage><epage>105</epage><pages>96-105</pages><issn>2378-8038</issn><issn>0023-852X</issn><eissn>2378-8038</eissn><abstract>Objective
Chronic rhinosinusitis (CRS) is a variable multifactorial disease. It can be divided into forms with nasal polyps (CRSwNP) and without (CRSsNP). Sinus and/or nasal polypectomy surgery are considered if maximal conservative treatment is insufficient. The predictive factors of the need of revision surgery comprise mostly the CRSwNP phenotype and are not fully understood.
Study Design
The aim of this follow‐up study was to evaluate the factors associated with the revision surgery rate in CRS patients with variable extent of disease.
Methods
Data of CRS patients (N = 178) undergoing sinus surgery and/or nasal polypectomy in 2001 to 2010 were used. Patient characteristics and follow‐up data were collected from patient records and questionnaires. Associations were analyzed by Fisher's exact, Mann Whitney U, and the Kaplan‐Meier method with log‐rank test. Unadjusted Cox's proportional hazard models were used for 12 variables and were fitted for the need for revision sinus surgery and/or nasal polypectomy during follow‐up of in average 9 years.
Results
The proportion of CRS patients who had undergone revision in 5 years was 9.6%. After adjustment, the following factors associated significantly with the need for recurrent CRS surgery: allergic rhinitis, corticosteroid treatment, previous surgery of CRS, and recurrent NP.
Conclusion
Increased risk of progressive CRS phenotypes with the need for revision surgery would putatively be recognized by relatively simple clinical questions. Further studies with increased sample size are needed to evaluate whether these predictive factors would be relevant for developing better detection and management of progressive CRS.
Level of Evidence
2b.</abstract><cop>United States</cop><pub>John Wiley & Sons, Inc</pub><pmid>28894807</pmid><doi>10.1002/lio2.27</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| source | Wiley Online Library Open Access; DOAJ Directory of Open Access Journals; Wiley Online Library Journals Frontfile Complete; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Allergy, Rhinology, and Immunology Antrochoanal polyp aspirin intolerance aspirin‐exacerbated respiratory disease Asthma Chronic illnesses Clinical trials Cystic fibrosis Endoscopy Genotype & phenotype Hospitals inflammation nasal polyp Nose Otolaryngology Patients Polyps Population recurrence revision surgery Rhinitis sinus surgery Sinuses Sinusitis Studies Surgery |
| title | Factors affecting revision rate of chronic rhinosinusitis |
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