Immune responses induced by heat killed Saccharomyces cerevisiae : A vaccine against fungal infection

Abstract Heat-killed Saccharomyces cerevisiae (HKY) used as a vaccine protects mice against systemic aspergillosis and coccidioidomycosis. Little is known about the immune response induced by HKY vaccination, consequently our goal was to do an analysis of HKY-induced immune responses involved in pro...

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Veröffentlicht in:	Vaccine 2011-02, Vol.29 (9), p.1745-1753
Hauptverfasser:	Liu, Min, Clemons, Karl V, Bigos, Marty, Medovarska, Izabela, Brummer, Elmer, Stevens, David A
Format:	Artikel
Sprache:	eng
Schlagworte:	Algae Allergy and Immunology Animals antibodies Antigens, Fungal - immunology Applied microbiology aspergillosis Aspergillosis - immunology Aspergillosis - prevention & control Aspergillus Biological and medical sciences blood serum cell division Cell growth cell proliferation cell-mediated immunity Chitinase coccidioidomycosis Coccidioidomycosis - immunology Coccidioidomycosis - prevention & control Cytokines enzyme-linked immunosorbent assay Experiments flow cytometry Fundamental and applied biological sciences. Psychology Fungal infection Fungal infections Fungal Vaccines - administration & dosage Fungal Vaccines - immunology fungi Gene expression glucans heat Hot Temperature Immune response Immune system interleukin-17 interleukin-6 Lymph nodes Lymph Nodes - cytology Lymph Nodes - immunology Lymph Nodes - microbiology Lymphocytes Male Mice Mice, Inbred BALB C Microbiology Miscellaneous Mycology Proteins Saccharomyces cerevisiae Saccharomyces cerevisiae - immunology Spleen Spleen - cytology Spleen - immunology Spleen - microbiology splenocytes Studies tumor necrosis factor-alpha vaccination Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Vaccines, Inactivated - administration & dosage Vaccines, Inactivated - immunology
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