A Population Pharmacokinetic Analysis to Study the Effect of Therapeutic Hypothermia on Vancomycin Disposition in Children Resuscitated From Cardiac Arrest

Limited data exist on the effects of therapeutic hypothermia on renal function and pharmacokinetics in pediatric patients after cardiac arrest. The objective was to describe the differences in vancomycin disposition in pediatric patients following cardiac arrest treated with either therapeutic hypot...

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Veröffentlicht in:	Pediatric critical care medicine 2017-07, Vol.18 (7), p.e290-e297
Hauptverfasser:	Zane, Nicole R, Reedy, Michael D, Gastonguay, Marc R, Himebauch, Adam S, Ramsey, Evan Z, Topjian, Alexis A, Zuppa, Athena F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Anti-Bacterial Agents - pharmacokinetics Anti-Bacterial Agents - therapeutic use Body Temperature Body Weight Child Child, Preschool Combined Modality Therapy Critical Care - methods Female Heart Arrest - metabolism Heart Arrest - therapy Humans Hypothermia, Induced Infant Kidney - physiology Male Metabolic Clearance Rate Models, Biological Resuscitation - methods Retrospective Studies Vancomycin - pharmacokinetics Vancomycin - therapeutic use
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