Functional characterization of the promoter of carbonyl reductase 1 gene in porcine endometrial cells

Prostaglandins (PGs) play a critical role in porcine reproduction, of which prostaglandin E2 (PGE2) and prostaglandin F2α (PGF2α) exert antiluteolytic and luteolysis actions, respectively. As a rate-limiting enzyme, carbonyl reductase 1 (CBR1) catalyzes the conversion of PGE2 to PGF2α. A high ratio...

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Veröffentlicht in:	Journal of Zhejiang University. B. Science 2017-07, Vol.18 (7), p.626-634
Hauptverfasser:	Zhang, Ai-ling, Sun, Xian-yue, Yin, Qi, Zeng, Jian-hua, Zhang, Zhe, Li, Jia-qi, Zhang, Hao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites bioinformatics Biomedical and Life Sciences Biomedicine Carbonyl Reductase (NADPH) - metabolism Carbonyls Catalysis Cbr1 gene Chromatin Chromatin Immunoprecipitation Cloning, Molecular Computational Biology Endometrium Endometrium - cytology Endometrium - metabolism Epithelial cells Epithelial Cells - metabolism Female Gene expression gene overexpression genes Immunoprecipitation Inflammation luciferase luteolysis NF-kappa B - metabolism NF-κB protein Overexpression precipitin tests Pregnancy Promoter Regions, Genetic Prostaglandin E2 Prostaglandins Reductase Regulatory sequences RNA, Small Interfering - metabolism Swine Transcription transcription (genetics) transcription factor NF-kappa B Transcription Factors - metabolism
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