PHRED-1 is a divergent neurexin-1 homolog that organizes muscle fibers and patterns organs during regeneration

Regeneration of body parts requires the replacement of multiple cell types. To dissect this complex process, we utilized planarian flatworms that are capable of regenerating any tissue after amputation. An RNAi screen for genes involved in regeneration of the pharynx identified a novel gene, Pharynx...

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Veröffentlicht in:	Developmental biology 2017-07, Vol.427 (1), p.165-175
Hauptverfasser:	Adler, Carolyn E., Sánchez Alvarado, Alejandro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Body Patterning - genetics Cell Adhesion Molecules, Neuronal - genetics Cell Adhesion Molecules, Neuronal - metabolism Gene Expression Regulation, Developmental Helminth Proteins - genetics Helminth Proteins - metabolism Immunohistochemistry In Situ Hybridization Lophotrochozoan Membrane Proteins - genetics Membrane Proteins - metabolism Microscopy, Confocal Muscle Muscle Fibers, Skeletal - metabolism Pharynx Pharynx - metabolism Pharynx - physiology Pharynx - surgery Planarians Planarians - genetics Planarians - metabolism Planarians - physiology Regeneration Regeneration - genetics Regeneration - physiology Reverse Transcriptase Polymerase Chain Reaction RNA Interference Transmembrane protein
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