Photoaffinity labeling of transcription factors by DNA-templated crosslinking

Characterization of transcription factor-DNA interaction is of high importance in elucidating the molecular mechanisms of gene transcriptions. DNA-based affinity probes were developed to capture and identify transcription factors by covalent crosslinking; however, the requirement of a crosslinker on...

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Veröffentlicht in:	Chemical science (Cambridge) 2015-01, Vol.6 (1), p.745-751
Hauptverfasser:	Liu, Ying, Zheng, Wenlu, Zhang, Wan, Chen, Nan, Liu, Yang, Chen, Li, Zhou, Xiaozhou, Chen, Xingshuo, Zheng, Haifeng, Li, Xiaoyu
Format:	Artikel
Sprache:	eng
Schlagworte:	Affinity Biology Chemistry Covalence Crosslinking Deoxyribonucleic acid Genes Proteins
Online-Zugang:	Volltext
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