Cardiovascular and cerebral hemodynamics during exercise and recovery in obese individuals as a function of their fitness status
The aim of this study was to compare cardiovascular hemodynamics and cerebral oxygenation/perfusion (COP) during and after maximal incremental exercise in obese individuals according to their aerobic fitness versus age‐matched healthy controls (AMHC). Fifty‐four middle–aged obese (OB) and 16 AMHC we...
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| description | The aim of this study was to compare cardiovascular hemodynamics and cerebral oxygenation/perfusion (COP) during and after maximal incremental exercise in obese individuals according to their aerobic fitness versus age‐matched healthy controls (AMHC). Fifty‐four middle–aged obese (OB) and 16 AMHC were recruited. Maximal cardiopulmonary function (gas exchange analysis), cardiac hemodynamics (impedance cardiography), and left frontal COP (near‐infrared spectroscopy: NIRS) were measured continuously during a maximal incremental ergocycle test. During recovery, reoxygenation/perfusion rate (ROPR: oxyhemoglobin: ΔO2Hb, deoxyhemoglobin: ΔHHb and total hemoglobin: ΔtHb; with NIRS) was also measured. Obese participants (OB, n = 54) were divided into two groups according to the median V˙O2 peak: the low‐fit obese (LF‐OB, n = 27) and the high‐fit obese (HF‐OB, n = 27). During exercise, end tidal pressure of CO2 (PETCO2), and COP (ΔO2Hb, ΔHHb and ΔtHb) did not differ between groups (OB, LF‐OB, HF‐OB, AMHC). During recovery, PETCO2 and ROPR (ΔO2Hb, ΔHHb and ΔtHb) were similar between the groups (OB, LF‐OB, HF‐OB, AMHC). During exercise and recovery, cardiac index was lower (P |
| doi_str_mv | 10.14814/phy2.13321 |
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The aim of this study was to compare cardiovascular and cerebral hemodynamics during and after maximal incremental exercise in low‐ and high‐fit obese subjects versus age‐matched healthy controls (AMHC). When compared to AMHC, obese groups have a similar cerebral vasodilatation by CO2 and cerebral hemodynamics during exercise and recovery. Obese subjects have a higher systolic blood pressure during exercise. Higher fitness in obese subjects may preserve their cardiopulmonary and cardiac function during exercise and recovery.</description><identifier>ISSN: 2051-817X</identifier><identifier>EISSN: 2051-817X</identifier><identifier>DOI: 10.14814/phy2.13321</identifier><identifier>PMID: 28642340</identifier><language>eng</language><publisher>United States: John Wiley & Sons, Inc</publisher><subject>Adipose Tissue and Obesity ; Aged ; Blood Pressure ; Carbon dioxide ; Cardiac and cerebral hemodynamics ; Cardiorespiratory Fitness ; Cardiovascular Physiology ; Central Nervous System ; Cerebrovascular Circulation ; Circulatory system ; Endurance and Performance ; Exercise ; Exercise Therapy - methods ; Female ; Gas exchange ; Gas Exchange and Transport ; Heart ; Hemodynamics ; Hemoglobin ; Hemoglobins - metabolism ; Human health and pathology ; Humans ; Infrared spectroscopy ; Life Sciences ; Male ; Middle Aged ; obesity ; Obesity - physiopathology ; Obesity - rehabilitation ; Obesity - therapy ; Original Research ; Oxygen Consumption ; Oxygenation ; Perfusion ; Physical fitness ; Physiology ; recovery ; Tissues and Organs ; Vasoconstriction</subject><ispartof>Physiological reports, 2017-06, Vol.5 (12), p.e13321-n/a</ispartof><rights>2017 The Authors. published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society</rights><rights>2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.</rights><rights>2017. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4861-24bab11e8419004d4407068da7a06caf7c68ce5aabf9df34d1c49c7dbcc0d24b3</citedby><cites>FETCH-LOGICAL-c4861-24bab11e8419004d4407068da7a06caf7c68ce5aabf9df34d1c49c7dbcc0d24b3</cites><orcidid>0000-0001-7273-8272</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492208/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492208/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,1417,11562,27924,27925,45574,45575,46052,46476,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28642340$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://u-bourgogne.hal.science/hal-01588561$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Gayda, Mathieu</creatorcontrib><creatorcontrib>Lapierre, Gabriel</creatorcontrib><creatorcontrib>Dupuy, Olivier</creatorcontrib><creatorcontrib>Fraser, Sarah</creatorcontrib><creatorcontrib>Bherer, Louis</creatorcontrib><creatorcontrib>Juneau, Martin</creatorcontrib><creatorcontrib>Gremeaux, Vincent</creatorcontrib><creatorcontrib>Nigam, Anil</creatorcontrib><title>Cardiovascular and cerebral hemodynamics during exercise and recovery in obese individuals as a function of their fitness status</title><title>Physiological reports</title><addtitle>Physiol Rep</addtitle><description>The aim of this study was to compare cardiovascular hemodynamics and cerebral oxygenation/perfusion (COP) during and after maximal incremental exercise in obese individuals according to their aerobic fitness versus age‐matched healthy controls (AMHC). Fifty‐four middle–aged obese (OB) and 16 AMHC were recruited. Maximal cardiopulmonary function (gas exchange analysis), cardiac hemodynamics (impedance cardiography), and left frontal COP (near‐infrared spectroscopy: NIRS) were measured continuously during a maximal incremental ergocycle test. During recovery, reoxygenation/perfusion rate (ROPR: oxyhemoglobin: ΔO2Hb, deoxyhemoglobin: ΔHHb and total hemoglobin: ΔtHb; with NIRS) was also measured. Obese participants (OB, n = 54) were divided into two groups according to the median V˙O2 peak: the low‐fit obese (LF‐OB, n = 27) and the high‐fit obese (HF‐OB, n = 27). During exercise, end tidal pressure of CO2 (PETCO2), and COP (ΔO2Hb, ΔHHb and ΔtHb) did not differ between groups (OB, LF‐OB, HF‐OB, AMHC). During recovery, PETCO2 and ROPR (ΔO2Hb, ΔHHb and ΔtHb) were similar between the groups (OB, LF‐OB, HF‐OB, AMHC). During exercise and recovery, cardiac index was lower (P < 0.05) in LF‐OB versus the other two groups (HF‐OB, AMHC). As well, systolic blood pressure was higher during exercise in the OB, LF‐OB and HF‐OB groups versus AMHC (P < 0.05). When compared to AMHC, obese individuals (OB, LF‐OB, HF‐OB) have a similar cerebral vasoreactivity by CO2 and cerebral hemodynamics during exercise and recovery, but a higher systolic blood pressure during exercise. Higher fitness in obese subjects (HF‐OB) seems to preserve their cardiopulmonary and cardiac function during exercise and recovery.
The aim of this study was to compare cardiovascular and cerebral hemodynamics during and after maximal incremental exercise in low‐ and high‐fit obese subjects versus age‐matched healthy controls (AMHC). When compared to AMHC, obese groups have a similar cerebral vasodilatation by CO2 and cerebral hemodynamics during exercise and recovery. Obese subjects have a higher systolic blood pressure during exercise. Higher fitness in obese subjects may preserve their cardiopulmonary and cardiac function during exercise and recovery.</description><subject>Adipose Tissue and Obesity</subject><subject>Aged</subject><subject>Blood Pressure</subject><subject>Carbon dioxide</subject><subject>Cardiac and cerebral hemodynamics</subject><subject>Cardiorespiratory Fitness</subject><subject>Cardiovascular Physiology</subject><subject>Central Nervous System</subject><subject>Cerebrovascular Circulation</subject><subject>Circulatory system</subject><subject>Endurance and Performance</subject><subject>Exercise</subject><subject>Exercise Therapy - methods</subject><subject>Female</subject><subject>Gas exchange</subject><subject>Gas Exchange and Transport</subject><subject>Heart</subject><subject>Hemodynamics</subject><subject>Hemoglobin</subject><subject>Hemoglobins - metabolism</subject><subject>Human health and pathology</subject><subject>Humans</subject><subject>Infrared spectroscopy</subject><subject>Life Sciences</subject><subject>Male</subject><subject>Middle Aged</subject><subject>obesity</subject><subject>Obesity - physiopathology</subject><subject>Obesity - rehabilitation</subject><subject>Obesity - therapy</subject><subject>Original Research</subject><subject>Oxygen Consumption</subject><subject>Oxygenation</subject><subject>Perfusion</subject><subject>Physical fitness</subject><subject>Physiology</subject><subject>recovery</subject><subject>Tissues and Organs</subject><subject>Vasoconstriction</subject><issn>2051-817X</issn><issn>2051-817X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>WIN</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9ksGL1DAUxoso7rLuybsEvLjIrHlp2qYXYRnUEQb0oKCnkCav2yxtMibtaG_-6Wam67LuQQgkvPd7X_Lyvix7DvQSuAD-ZtfN7BLynMGj7JTRAlYCqm-P751PsvMYbyilQPO8pvxpdsJEyVnO6Wn2e62CsX6vop56FYhyhmgM2ATVkw4Hb2anBqsjMVOw7prgLwzaRjySAbXfY5iJdcQ3mKLWGbu3ZlJ9JCot0k5Oj9anfEvGDm0grR0dxkjiqMYpPsuetAnG89v9LPv6_t2X9Wa1_fTh4_pqu9JclLBivFENAAoONaXccE4rWgqjKkVLrdpKl0JjoVTT1qbNuQHNa12ZRmtqUnF-lr1ddHdTM6DR6MbUotwFO6gwS6-s_DfjbCev_V4WvGaMiiRwsQh0D8o2V1t5iFEohChK2ENiX91eFvyPCeMoBxs19r1y6KcooU4Tq5lgB_TlA_TGT8Glr5CM5kUOdc15ol4vlA4-xoDt3QuAyqMR5MEI8miERL-43-sd-3fsCWAL8NP2OP9PS37efGeL6h__asB0</recordid><startdate>201706</startdate><enddate>201706</enddate><creator>Gayda, Mathieu</creator><creator>Lapierre, Gabriel</creator><creator>Dupuy, Olivier</creator><creator>Fraser, Sarah</creator><creator>Bherer, Louis</creator><creator>Juneau, Martin</creator><creator>Gremeaux, Vincent</creator><creator>Nigam, Anil</creator><general>John Wiley & Sons, Inc</general><general>Wiley</general><general>John Wiley and Sons Inc</general><scope>24P</scope><scope>WIN</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7T5</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>1XC</scope><scope>VOOES</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-7273-8272</orcidid></search><sort><creationdate>201706</creationdate><title>Cardiovascular and cerebral hemodynamics during exercise and recovery in obese individuals as a function of their fitness status</title><author>Gayda, Mathieu ; Lapierre, Gabriel ; Dupuy, Olivier ; Fraser, Sarah ; Bherer, Louis ; Juneau, Martin ; Gremeaux, Vincent ; Nigam, Anil</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4861-24bab11e8419004d4407068da7a06caf7c68ce5aabf9df34d1c49c7dbcc0d24b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adipose Tissue and Obesity</topic><topic>Aged</topic><topic>Blood Pressure</topic><topic>Carbon dioxide</topic><topic>Cardiac and cerebral hemodynamics</topic><topic>Cardiorespiratory Fitness</topic><topic>Cardiovascular Physiology</topic><topic>Central Nervous System</topic><topic>Cerebrovascular Circulation</topic><topic>Circulatory system</topic><topic>Endurance and Performance</topic><topic>Exercise</topic><topic>Exercise Therapy - methods</topic><topic>Female</topic><topic>Gas exchange</topic><topic>Gas Exchange and Transport</topic><topic>Heart</topic><topic>Hemodynamics</topic><topic>Hemoglobin</topic><topic>Hemoglobins - metabolism</topic><topic>Human health and pathology</topic><topic>Humans</topic><topic>Infrared spectroscopy</topic><topic>Life Sciences</topic><topic>Male</topic><topic>Middle Aged</topic><topic>obesity</topic><topic>Obesity - physiopathology</topic><topic>Obesity - rehabilitation</topic><topic>Obesity - therapy</topic><topic>Original Research</topic><topic>Oxygen Consumption</topic><topic>Oxygenation</topic><topic>Perfusion</topic><topic>Physical fitness</topic><topic>Physiology</topic><topic>recovery</topic><topic>Tissues and Organs</topic><topic>Vasoconstriction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gayda, Mathieu</creatorcontrib><creatorcontrib>Lapierre, Gabriel</creatorcontrib><creatorcontrib>Dupuy, Olivier</creatorcontrib><creatorcontrib>Fraser, Sarah</creatorcontrib><creatorcontrib>Bherer, Louis</creatorcontrib><creatorcontrib>Juneau, Martin</creatorcontrib><creatorcontrib>Gremeaux, Vincent</creatorcontrib><creatorcontrib>Nigam, Anil</creatorcontrib><collection>Wiley Online Library (Open Access Collection)</collection><collection>Wiley Online Library (Open Access Collection)</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Biological Science Database</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>Hyper Article en Ligne (HAL) (Open Access)</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Physiological reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gayda, Mathieu</au><au>Lapierre, Gabriel</au><au>Dupuy, Olivier</au><au>Fraser, Sarah</au><au>Bherer, Louis</au><au>Juneau, Martin</au><au>Gremeaux, Vincent</au><au>Nigam, Anil</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cardiovascular and cerebral hemodynamics during exercise and recovery in obese individuals as a function of their fitness status</atitle><jtitle>Physiological reports</jtitle><addtitle>Physiol Rep</addtitle><date>2017-06</date><risdate>2017</risdate><volume>5</volume><issue>12</issue><spage>e13321</spage><epage>n/a</epage><pages>e13321-n/a</pages><issn>2051-817X</issn><eissn>2051-817X</eissn><abstract>The aim of this study was to compare cardiovascular hemodynamics and cerebral oxygenation/perfusion (COP) during and after maximal incremental exercise in obese individuals according to their aerobic fitness versus age‐matched healthy controls (AMHC). Fifty‐four middle–aged obese (OB) and 16 AMHC were recruited. Maximal cardiopulmonary function (gas exchange analysis), cardiac hemodynamics (impedance cardiography), and left frontal COP (near‐infrared spectroscopy: NIRS) were measured continuously during a maximal incremental ergocycle test. During recovery, reoxygenation/perfusion rate (ROPR: oxyhemoglobin: ΔO2Hb, deoxyhemoglobin: ΔHHb and total hemoglobin: ΔtHb; with NIRS) was also measured. Obese participants (OB, n = 54) were divided into two groups according to the median V˙O2 peak: the low‐fit obese (LF‐OB, n = 27) and the high‐fit obese (HF‐OB, n = 27). During exercise, end tidal pressure of CO2 (PETCO2), and COP (ΔO2Hb, ΔHHb and ΔtHb) did not differ between groups (OB, LF‐OB, HF‐OB, AMHC). During recovery, PETCO2 and ROPR (ΔO2Hb, ΔHHb and ΔtHb) were similar between the groups (OB, LF‐OB, HF‐OB, AMHC). During exercise and recovery, cardiac index was lower (P < 0.05) in LF‐OB versus the other two groups (HF‐OB, AMHC). As well, systolic blood pressure was higher during exercise in the OB, LF‐OB and HF‐OB groups versus AMHC (P < 0.05). When compared to AMHC, obese individuals (OB, LF‐OB, HF‐OB) have a similar cerebral vasoreactivity by CO2 and cerebral hemodynamics during exercise and recovery, but a higher systolic blood pressure during exercise. Higher fitness in obese subjects (HF‐OB) seems to preserve their cardiopulmonary and cardiac function during exercise and recovery.
The aim of this study was to compare cardiovascular and cerebral hemodynamics during and after maximal incremental exercise in low‐ and high‐fit obese subjects versus age‐matched healthy controls (AMHC). When compared to AMHC, obese groups have a similar cerebral vasodilatation by CO2 and cerebral hemodynamics during exercise and recovery. Obese subjects have a higher systolic blood pressure during exercise. Higher fitness in obese subjects may preserve their cardiopulmonary and cardiac function during exercise and recovery.</abstract><cop>United States</cop><pub>John Wiley & Sons, Inc</pub><pmid>28642340</pmid><doi>10.14814/phy2.13321</doi><tpages>13</tpages><orcidid>https://orcid.org/0000-0001-7273-8272</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Adipose Tissue and Obesity Aged Blood Pressure Carbon dioxide Cardiac and cerebral hemodynamics Cardiorespiratory Fitness Cardiovascular Physiology Central Nervous System Cerebrovascular Circulation Circulatory system Endurance and Performance Exercise Exercise Therapy - methods Female Gas exchange Gas Exchange and Transport Heart Hemodynamics Hemoglobin Hemoglobins - metabolism Human health and pathology Humans Infrared spectroscopy Life Sciences Male Middle Aged obesity Obesity - physiopathology Obesity - rehabilitation Obesity - therapy Original Research Oxygen Consumption Oxygenation Perfusion Physical fitness Physiology recovery Tissues and Organs Vasoconstriction |
| title | Cardiovascular and cerebral hemodynamics during exercise and recovery in obese individuals as a function of their fitness status |
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