Breast cancer detection and tumor characteristics in BRCA1 and BRCA2 mutation carriers

Purpose To describe imaging findings, detection rates, and tumor characteristics of breast cancers in a large series of patients with BRCA1 and BRCA2 mutations to potentially streamline screening strategies. Methods An IRB-approved, HIPAA-compliant retrospective analysis of 496 BRCA mutation carrier...

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Veröffentlicht in:	Breast cancer research and treatment 2017-06, Vol.163 (3), p.565-571
Hauptverfasser:	Krammer, Julia, Pinker-Domenig, Katja, Robson, Mark E., Gönen, Mithat, Bernard-Davila, Blanca, Morris, Elizabeth A., Mangino, Debra A., Jochelson, Maxine S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged BRCA1 protein BRCA1 Protein - genetics BRCA2 protein BRCA2 Protein - genetics Breast cancer Breast carcinoma Breast Neoplasms - diagnostic imaging Breast Neoplasms - genetics Breast Neoplasms - pathology Cancer diagnosis Cancer genetics Cancer research Carcinoma, Intraductal, Noninfiltrating - diagnostic imaging Carcinoma, Intraductal, Noninfiltrating - genetics Carcinoma, Intraductal, Noninfiltrating - pathology Comparative analysis Ductal carcinoma in situ Electronic medical records Epidemiology Female Gene mutation Genetic aspects Genetic Carrier Screening Health aspects Heterozygote Hormone replacement therapy Humans Invasiveness Magnetic Resonance Imaging Mammography Mastectomy Medical records Medicine Medicine & Public Health Middle Aged Mutation Neoplasm Staging Oncology Right of privacy Risk factors Tumors
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