Antifungal activity of terrestrial Streptomyces rochei strain HF391 against clinical azole -resistant Aspergillus fumigatus
Actinomycetes have been discovered as source of antifungal compounds that are currently in clinical use. Invasive aspergillosis (IA) due to has been identified as individual drug-resistant to be an emerging pathogen opportunities a global scale. This paper described the antifungal activity of one te...
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| Veröffentlicht in: | Current Medical Mycology 2015-06, Vol.1 (2), p.19-24 |
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| creator | Hadizadeh, S Forootanfar, H Shahidi Bonjar, G H Falahati Nejad, M Karamy Robati, A Ayatollahi Mousavi, S A Amirporrostami, S |
| description | Actinomycetes have been discovered as source of antifungal compounds that are currently in clinical use. Invasive aspergillosis (IA) due to
has been identified as individual drug-resistant
to be an emerging pathogen opportunities a global scale. This paper described the antifungal activity of one terrestrial actinomycete against the clinically isolated azole-resistant
.
Soil samples were collected from various locations of Kerman, Iran. Thereafter, the actinomycetes were isolated using starch-casein-nitrate-agar medium and the most efficient actinomycetes (capable of inhibiting
) were screened using agar block method. In the next step, the selected actinomycete was cultivated in starch-casein- broth medium and the inhibitory activity of the obtained culture broth was evaluated using agar well diffusion method.
The selected actinomycete, identified as
strain HF391, could suppress the growth of
isolates which was isolated from the clinical samples of patients treated with azoles. This strain showed higher inhibition zones on agar diffusion assay which was more than 15 mm.
The obtained results of the present study introduced
strain HF391 as terrestrial actinomycete that can inhibit the growth of clinically isolated |
| doi_str_mv | 10.18869/acadpub.cmm.1.2.19 |
| format | Article |
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has been identified as individual drug-resistant
to be an emerging pathogen opportunities a global scale. This paper described the antifungal activity of one terrestrial actinomycete against the clinically isolated azole-resistant
.
Soil samples were collected from various locations of Kerman, Iran. Thereafter, the actinomycetes were isolated using starch-casein-nitrate-agar medium and the most efficient actinomycetes (capable of inhibiting
) were screened using agar block method. In the next step, the selected actinomycete was cultivated in starch-casein- broth medium and the inhibitory activity of the obtained culture broth was evaluated using agar well diffusion method.
The selected actinomycete, identified as
strain HF391, could suppress the growth of
isolates which was isolated from the clinical samples of patients treated with azoles. This strain showed higher inhibition zones on agar diffusion assay which was more than 15 mm.
The obtained results of the present study introduced
strain HF391 as terrestrial actinomycete that can inhibit the growth of clinically isolated</description><identifier>ISSN: 2423-3439</identifier><identifier>EISSN: 2423-3420</identifier><identifier>EISSN: 3420-2423</identifier><identifier>DOI: 10.18869/acadpub.cmm.1.2.19</identifier><identifier>PMID: 28680984</identifier><language>eng</language><publisher>Iran: Iranian Society of Medical Mycology</publisher><subject>Actinomycetes ; Antifungal Agents ; Aspergillus fumigatus ; Azoles resistant ; Original</subject><ispartof>Current Medical Mycology, 2015-06, Vol.1 (2), p.19-24</ispartof><rights>Copyright© 2015, Published by Mazandaran University of Medical Sciences on behalf of Iranian Society of Medical Mycology and Invasive Fungi Research Center.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3169-ac462dff9be24f131137aa3d571c4f4a943aba5c166acc62adc2b8bec46ea8583</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490309/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490309/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28680984$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hadizadeh, S</creatorcontrib><creatorcontrib>Forootanfar, H</creatorcontrib><creatorcontrib>Shahidi Bonjar, G H</creatorcontrib><creatorcontrib>Falahati Nejad, M</creatorcontrib><creatorcontrib>Karamy Robati, A</creatorcontrib><creatorcontrib>Ayatollahi Mousavi, S A</creatorcontrib><creatorcontrib>Amirporrostami, S</creatorcontrib><creatorcontrib>Department of Medical Mycology & Parasitology, Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran</creatorcontrib><creatorcontrib>Herbal and Traditional Medicines Research Center, Kerman University of Medical Sciences, Kerman, Iran</creatorcontrib><creatorcontrib>Department of Plant Pathology & Biotechnology, College of Agriculture, Bahonar University of Kerman, Iran</creatorcontrib><creatorcontrib>Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran</creatorcontrib><title>Antifungal activity of terrestrial Streptomyces rochei strain HF391 against clinical azole -resistant Aspergillus fumigatus</title><title>Current Medical Mycology</title><addtitle>Curr Med Mycol</addtitle><description>Actinomycetes have been discovered as source of antifungal compounds that are currently in clinical use. Invasive aspergillosis (IA) due to
has been identified as individual drug-resistant
to be an emerging pathogen opportunities a global scale. This paper described the antifungal activity of one terrestrial actinomycete against the clinically isolated azole-resistant
.
Soil samples were collected from various locations of Kerman, Iran. Thereafter, the actinomycetes were isolated using starch-casein-nitrate-agar medium and the most efficient actinomycetes (capable of inhibiting
) were screened using agar block method. In the next step, the selected actinomycete was cultivated in starch-casein- broth medium and the inhibitory activity of the obtained culture broth was evaluated using agar well diffusion method.
The selected actinomycete, identified as
strain HF391, could suppress the growth of
isolates which was isolated from the clinical samples of patients treated with azoles. This strain showed higher inhibition zones on agar diffusion assay which was more than 15 mm.
The obtained results of the present study introduced
strain HF391 as terrestrial actinomycete that can inhibit the growth of clinically isolated</description><subject>Actinomycetes</subject><subject>Antifungal Agents</subject><subject>Aspergillus fumigatus</subject><subject>Azoles resistant</subject><subject>Original</subject><issn>2423-3439</issn><issn>2423-3420</issn><issn>3420-2423</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNpVkd1KHTEUhYNYVNQnKJS8wEzzNzPJjXAQrYLQi9brsCeTjCkzk0OSEU59eaPHHurV3uzF-jashdBXSmoqZau-g4Fhu_a1meea1qym6gidMcF4xQUjx4edq1N0mZLvSUM6ThohTtApk60kSooz9LJZsnfrMsKEwWT_7PMOB4ezjdGmHH25_8rRbnOYd8YmHIN5sh4XCfyC7265ohjGsqeMzeQXb95If8NkcVUIPmVYMt6krY2jn6Y1YbfOfoS8pgv0xcGU7OXHPEePtze_r--qh58_7q83D5XhtFUVGNGywTnVWyYc5ZTyDoAPTUeNcAKU4NBDY2jbgjEtg8GwXva22CzIRvJzdL_nDgH-6G30M8SdDuD1-yHEUUPM3kxWc9n1HWGMAQXBukESKKFJ17qmcaSnhXW1Z5XsZzsYu5Qgpk_Qz8rin_QYnnUjFOFEFQDfA0wMKUXrDl5K9Hu1-qNaXarVVDNN31zf_n978Pwrkr8CmounBA</recordid><startdate>20150601</startdate><enddate>20150601</enddate><creator>Hadizadeh, S</creator><creator>Forootanfar, H</creator><creator>Shahidi Bonjar, G H</creator><creator>Falahati Nejad, M</creator><creator>Karamy Robati, A</creator><creator>Ayatollahi Mousavi, S A</creator><creator>Amirporrostami, S</creator><general>Iranian Society of Medical Mycology</general><general>Mazandaran University of Medical Sciences</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20150601</creationdate><title>Antifungal activity of terrestrial Streptomyces rochei strain HF391 against clinical azole -resistant Aspergillus fumigatus</title><author>Hadizadeh, S ; Forootanfar, H ; Shahidi Bonjar, G H ; Falahati Nejad, M ; Karamy Robati, A ; Ayatollahi Mousavi, S A ; Amirporrostami, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3169-ac462dff9be24f131137aa3d571c4f4a943aba5c166acc62adc2b8bec46ea8583</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Actinomycetes</topic><topic>Antifungal Agents</topic><topic>Aspergillus fumigatus</topic><topic>Azoles resistant</topic><topic>Original</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hadizadeh, S</creatorcontrib><creatorcontrib>Forootanfar, H</creatorcontrib><creatorcontrib>Shahidi Bonjar, G H</creatorcontrib><creatorcontrib>Falahati Nejad, M</creatorcontrib><creatorcontrib>Karamy Robati, A</creatorcontrib><creatorcontrib>Ayatollahi Mousavi, S A</creatorcontrib><creatorcontrib>Amirporrostami, S</creatorcontrib><creatorcontrib>Department of Medical Mycology & Parasitology, Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran</creatorcontrib><creatorcontrib>Herbal and Traditional Medicines Research Center, Kerman University of Medical Sciences, Kerman, Iran</creatorcontrib><creatorcontrib>Department of Plant Pathology & Biotechnology, College of Agriculture, Bahonar University of Kerman, Iran</creatorcontrib><creatorcontrib>Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Current Medical Mycology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hadizadeh, S</au><au>Forootanfar, H</au><au>Shahidi Bonjar, G H</au><au>Falahati Nejad, M</au><au>Karamy Robati, A</au><au>Ayatollahi Mousavi, S A</au><au>Amirporrostami, S</au><aucorp>Department of Medical Mycology & Parasitology, Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran</aucorp><aucorp>Herbal and Traditional Medicines Research Center, Kerman University of Medical Sciences, Kerman, Iran</aucorp><aucorp>Department of Plant Pathology & Biotechnology, College of Agriculture, Bahonar University of Kerman, Iran</aucorp><aucorp>Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antifungal activity of terrestrial Streptomyces rochei strain HF391 against clinical azole -resistant Aspergillus fumigatus</atitle><jtitle>Current Medical Mycology</jtitle><addtitle>Curr Med Mycol</addtitle><date>2015-06-01</date><risdate>2015</risdate><volume>1</volume><issue>2</issue><spage>19</spage><epage>24</epage><pages>19-24</pages><issn>2423-3439</issn><eissn>2423-3420</eissn><eissn>3420-2423</eissn><abstract>Actinomycetes have been discovered as source of antifungal compounds that are currently in clinical use. Invasive aspergillosis (IA) due to
has been identified as individual drug-resistant
to be an emerging pathogen opportunities a global scale. This paper described the antifungal activity of one terrestrial actinomycete against the clinically isolated azole-resistant
.
Soil samples were collected from various locations of Kerman, Iran. Thereafter, the actinomycetes were isolated using starch-casein-nitrate-agar medium and the most efficient actinomycetes (capable of inhibiting
) were screened using agar block method. In the next step, the selected actinomycete was cultivated in starch-casein- broth medium and the inhibitory activity of the obtained culture broth was evaluated using agar well diffusion method.
The selected actinomycete, identified as
strain HF391, could suppress the growth of
isolates which was isolated from the clinical samples of patients treated with azoles. This strain showed higher inhibition zones on agar diffusion assay which was more than 15 mm.
The obtained results of the present study introduced
strain HF391 as terrestrial actinomycete that can inhibit the growth of clinically isolated</abstract><cop>Iran</cop><pub>Iranian Society of Medical Mycology</pub><pmid>28680984</pmid><doi>10.18869/acadpub.cmm.1.2.19</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Actinomycetes Antifungal Agents Aspergillus fumigatus Azoles resistant Original |
| title | Antifungal activity of terrestrial Streptomyces rochei strain HF391 against clinical azole -resistant Aspergillus fumigatus |
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