TET1-mediated DNA hypomethylation regulates the expression of MUC4 in lung cancer

Lung cancer remains a disease of high mortality, despite advanced diagnostic techniques. Mucins (MUC) play crucial roles in carcinogenesis and tumor invasion in lung neoplasms. Our immunohistochemistry (IHC) studies have shown that high MUC4 expression correlates with a poor outcome. We have also sh...

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Veröffentlicht in:	Genes & cancer 2017-03, Vol.8 (3-4), p.517-527
Hauptverfasser:	Yokoyama, Seiya, Higashi, Michiyo, Tsutsumida, Hideaki, Wakimoto, Jouji, Hamada, Tomofumi, Wiest, Edwin, Matsuo, Kei, Kitazono, Ikumi, Goto, Yuko, Guo, Xin, Hamada, Taiji, Yamada, Sohsuke, Hiraki, Tsubasa, Yonezawa, Suguru, Batra, Surinder K, Hollingsworth, Michael A, Tanimoto, Akihide
Format:	Artikel
Sprache:	eng
Schlagworte:	Research Paper
Online-Zugang:	Volltext
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