Topography of calcium phosphate ceramics regulates primary cilia length and TGF receptor recruitment associated with osteogenesis

[Display omitted] The surface topography of synthetic biomaterials is known to play a role in material-driven osteogenesis. Recent studies show that TGFβ signalling also initiates osteogenic differentiation. TGFβ signalling requires the recruitment of TGFβ receptors (TGFβR) to the primary cilia. In...

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Veröffentlicht in:Acta biomaterialia 2017-07, Vol.57, p.487-497
Hauptverfasser: Zhang, Jingwei, Dalbay, Melis T., Luo, Xiaoman, Vrij, Erik, Barbieri, Davide, Moroni, Lorenzo, de Bruijn, Joost D., van Blitterswijk, Clemens A., Chapple, J. Paul, Knight, Martin M., Yuan, Huipin
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Sprache:eng
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