Upregulation of miR-125b is associated with poor prognosis and trastuzumab resistance in HER2-positive gastric cancer

Gastric cancer is one of the most common types of human cancer associated with a poor prognosis. MicroRNAs (miRs), a class of non-coding RNAs that are 18-25 nucleotides in length, act as key regulators in gene expression, and have been implicated in various human cancer types. miR-125b has been impl...

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Veröffentlicht in:	Experimental and therapeutic medicine 2017-07, Vol.14 (1), p.657-663
Hauptverfasser:	Sui, Minghua, Jiao, Aihong, Zhai, Huiyuan, Wang, Yan, Wang, Yong, Sun, Dengjun, Li, Peng
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Breast cancer Clinical outcomes Drug resistance Drug therapy Epidermal growth factor Gastric cancer Gene expression Genetic aspects Genetic regulation Health aspects Hybridization Immunotherapy Lung cancer Lymphatic system Medical prognosis Metastasis MicroRNAs Monoclonal antibodies Standard deviation Stomach cancer Studies Targeted cancer therapy Testing Trastuzumab
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