Gastric cancer-derived heat shock protein-gp96 peptide complex enhances dendritic cell activation

AIM To investigate the role of heat shock protein(HSP)-glycoprotein(gp)96 in dendritic cells(DCs)and lymphocytes induction in gastric cancer(GC). METHODS Human GC cell lines KATOIII,MKN-28 and SGC-7901were infected with adenovirus gp96 at a multiplicity of infection of 100.gp96-GC antigen peptide co...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2017-06, Vol.23 (24), p.4390-4398
Hauptverfasser:	Lu, Wen-Wen, Zhang, Hong, Li, You-Ming, Ji, Feng
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae - genetics Antigen Presentation - immunology Antigens, Neoplasm - immunology Basic Study Cell Line, Tumor Cell Proliferation Coculture Techniques Cytokines - metabolism Dendritic Cells - immunology Enzyme-Linked Immunosorbent Assay Genetic Vectors Heat-Shock Proteins - immunology Humans Killer Cells, Natural - immunology Killer Cells, Natural - metabolism Lymphocyte Activation - immunology Membrane Glycoproteins - immunology Stomach Neoplasms - immunology T-Lymphocytes, Cytotoxic - immunology T-Lymphocytes, Cytotoxic - metabolism
Online-Zugang:	Volltext
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