Biosynthesis of Modular Ascarosides in C. elegans

The nematode Caenorhabditis elegans uses simple building blocks from primary metabolism and a strategy of modular assembly to build a great diversity of signaling molecules, the ascarosides, which function as a chemical language in this model organism. In the ascarosides, the dideoxysugar ascarylose...

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Veröffentlicht in:	Angewandte Chemie International Edition 2017-04, Vol.56 (17), p.4729-4733
Hauptverfasser:	Panda, Oishika, Akagi, Allison E., Artyukhin, Alexander B., Judkins, Joshua C., Le, Henry H., Mahanti, Parag, Cohen, Sarah M., Sternberg, Paul W., Schroeder, Frank C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Assembly Biosynthesis chemical signaling Metabolism metabolites Mutants natural products Nematodes Organelles pheromones Signaling Waste disposal
Online-Zugang:	Volltext
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