The Roles of Long Non-Protein-Coding RNAs in Osteo-Adipogenic Lineage Commitment

Osteoblasts and adipocytes share a common mesenchymal progenitor in the bone marrow. This implies that a reciprocal relationship exists between osteogenic and adipogenic differentiation. Further, cells of osteoblast lineage transdifferentiate into adipocytes under some circumstances. Dysregulation o...

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Veröffentlicht in:	International journal of molecular sciences 2017-06, Vol.18 (6), p.1236
Hauptverfasser:	Yoshioka, Hirotaka, Yoshiko, Yuji
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adipocytes - cytology Adipocytes - metabolism Adipogenesis Adipogenesis - genetics Adipose tissue Animals Biomedical materials Bone diseases Bone marrow Bone turnover Cell differentiation Cell Lineage - genetics Cell Transdifferentiation - genetics Chromatin Coding Crosstalk DNA methylation Epigenesis, Genetic Epigenetics Gene Expression Regulation Gene regulation Histones Homeostasis Humans Kinases Mesenchyme Non-coding RNA Osteoblastogenesis Osteoblasts Osteoblasts - cytology Osteoblasts - metabolism Osteogenesis - genetics Osteoporosis Post-translation Proteins Review RNA, Long Noncoding - genetics Stem cells Transcription factors Transforming Growth Factor beta - metabolism Wnt Proteins - metabolism
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