Depigmenting Effect of Resveratrol Is Dependent on FOXO3a Activation without SIRT1 Activation

Resveratrol exhibits not only anti-melanogenic property by inhibiting microphthalmia-associated transcription factor (MITF), but also anti-aging property by activating sirtuin-1 (SIRT1). In this study, the relationship between depigmenting effect of resveratrol and SIRT1/forkhead box O (FOXO) 3a act...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of molecular sciences 2017-06, Vol.18 (6), p.1213
Hauptverfasser:	Kwon, Soon-Hyo, Choi, Hye-Ryung, Kang, Youn-A, Park, Kyoung-Chan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Antioxidants Cell cycle Cell Line, Tumor Forkhead Box Protein O3 - agonists Forkhead protein FOXO3 protein Growth factors Humans Inhibitors Insulin Investigations Kinases Melanins - metabolism Melanocytes Melanocytes - drug effects Melanocytes - metabolism Metabolic pathways Microphthalmia-associated transcription factor Monophenol Monooxygenase - metabolism Oxidative stress Oxidative Stress - drug effects Proteins Reactive Oxygen Species - metabolism Resveratrol SIRT1 protein Sirtuin 1 - metabolism Skin Lightening Preparations - pharmacology Stilbenes - pharmacology Superoxide Dismutase - metabolism Transcription factors Tyrosinase
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!