Impact of hysterosalpingography after operative treatment for ectopic pregnancy in Taiwan: A 16-year Nationwide Population-Based Analysis
By retrieving records from Taiwan's National Health Insurance (NHI) system's database, the current study aimed to investigate the impacts of hysterosalpingography (HSG) to patients after ectopic pregnancy (EP) operations in Taiwan.In this retrospective cohort study, insurance claims data f...
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| Veröffentlicht in: | Medicine (Baltimore) 2017-06, Vol.96 (25), p.e7263-e7263 |
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| creator | Chiu, Nai-Chi Ho, Chi-Hong Shen, Shu-Huei Tsuei, Yu-Chuan Lee, Kang-Lung Huang, Chen-Yu Li, Hsin-Yang Chen, Tzeng-Ji |
| description | By retrieving records from Taiwan's National Health Insurance (NHI) system's database, the current study aimed to investigate the impacts of hysterosalpingography (HSG) to patients after ectopic pregnancy (EP) operations in Taiwan.In this retrospective cohort study, insurance claims data from 1997 to 2013, derived from a cohort of 1 million people randomly sampled to represent all NHI beneficiaries, were analyzed. Patients after ectopic pregnancy (EP) operations were identified via the inclusion of the corresponding NHI procedure codes. We further divided the patients into 2 groups by whether received subsequent HSG, EP-HSG, and EP-no-HSG. Patients with history of previous pregnancies (PP) and subsequent HSG were grouped as PP-HSG. We sought to evaluate the following pregnancies (FP) rate, interval to FP in EP-HSG compared with that in EP-no-HSG, and PP-HSG.EP-HSG had significantly higher FP rate odds ratio than EP-no-HSG (OR, 1.64; 95% CI, 1.24-2.16, P 25 years old: 0.47, 0.38-0.57; >30 years old: 0.29, 0.24-0.35; >35 years old: 0.12, 0.08-0.18, all P |
| doi_str_mv | 10.1097/MD.0000000000007263 |
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| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5484238</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1912617565</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3559-60013a4cd0b599f04cc3730f3bda1d6db7b5514a0e8d8105c4d04de2e9046da63</originalsourceid><addsrcrecordid>eNpdUU1v1DAQtRCILoVfgIR85JJixx9JOCAtLR-VWuBQztbEnmwM2TjYSVf5Cf3XzXZLVfDFmuf33sz4EfKasxPOquLd5dkJe3SKXIsnZMWV0JmqtHxKVozlKiuqQh6RFyn9YoyLIpfPyVFearkUbEVuzrcD2JGGhrZzGjGGBN3g-03YRBjamUKzgDQMGGH010jHiDBusR9pEyJFO4bBWzpE3PTQ25n6nl6B30H_nq4p19mMEOm3RRv6nXdIf4Rh6u7K7CMkdHTdQzcnn16SZw10CV_d38fk5-dPV6dfs4vvX85P1xeZFUpVmd5vAdI6Vquqapi0VhSCNaJ2wJ12dVErxSUwLF3JmbLSMekwx4pJ7UCLY_Lh4DtM9RadXVaJ0Jkh-i3E2QTw5t-X3rdmE66NkqXMRbkYvL03iOHPhGk0W58sdh30GKZkeMVzzQul1UIVB6pd_jVFbB7acGb2IZrLM_N_iIvqzeMJHzR_U1sI8kDYhW5JJ_3uph1G0yJ0Y3vnp4oqz3LGC6ZzwbI9Uolb9lmqiQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1912617565</pqid></control><display><type>article</type><title>Impact of hysterosalpingography after operative treatment for ectopic pregnancy in Taiwan: A 16-year Nationwide Population-Based Analysis</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Wolters Kluwer Open Health</source><source>IngentaConnect Free/Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Chiu, Nai-Chi ; Ho, Chi-Hong ; Shen, Shu-Huei ; Tsuei, Yu-Chuan ; Lee, Kang-Lung ; Huang, Chen-Yu ; Li, Hsin-Yang ; Chen, Tzeng-Ji</creator><creatorcontrib>Chiu, Nai-Chi ; Ho, Chi-Hong ; Shen, Shu-Huei ; Tsuei, Yu-Chuan ; Lee, Kang-Lung ; Huang, Chen-Yu ; Li, Hsin-Yang ; Chen, Tzeng-Ji</creatorcontrib><description>By retrieving records from Taiwan's National Health Insurance (NHI) system's database, the current study aimed to investigate the impacts of hysterosalpingography (HSG) to patients after ectopic pregnancy (EP) operations in Taiwan.In this retrospective cohort study, insurance claims data from 1997 to 2013, derived from a cohort of 1 million people randomly sampled to represent all NHI beneficiaries, were analyzed. Patients after ectopic pregnancy (EP) operations were identified via the inclusion of the corresponding NHI procedure codes. We further divided the patients into 2 groups by whether received subsequent HSG, EP-HSG, and EP-no-HSG. Patients with history of previous pregnancies (PP) and subsequent HSG were grouped as PP-HSG. We sought to evaluate the following pregnancies (FP) rate, interval to FP in EP-HSG compared with that in EP-no-HSG, and PP-HSG.EP-HSG had significantly higher FP rate odds ratio than EP-no-HSG (OR, 1.64; 95% CI, 1.24-2.16, P < .001). EP-HSG had lower FP rate odds ratio than that in PP-HSG, but no significant difference (33.1% vs 34.6%, P = .654). The INTERVAL(HSG-FP) in EP-HSG was no significantly different from that in PP-HSG (843.34 ± 82 days vs 644.72 ± 24.30 days, P = .077). There was significant positive correlation between FP after EP and number of HSG (r = 0.070, P < .001). There were significant negative correlation between FP and EP age (r = -0.270, P < .001), FP and INTERVAL(EP-HSG) (r = -0.212, P = .001). The multivariate analysis showed that INTERVAL(EP-HSG) less than 1 year is the predictor factor of INTERVAL(EP-FP) (hazard ratio: 1.422; 95% CI: 1.130-1.788; P = .003). It was evident that the longer the INTERVAL(EP-HSG), the lower the FP rate odds ratio; and the older the EP age, the lower the FP rate odds ratio. (OR, 95% CI; >1 year: 0.59, 0.41-0.86; >2 year: 0.42, 0.32-0.55; >25 years old: 0.47, 0.38-0.57; >30 years old: 0.29, 0.24-0.35; >35 years old: 0.12, 0.08-0.18, all P < .001).Receiving HSG after EP, short INTERVAL(EP-HSG), EP age less than 30 years old, had significant positive impacts on the FP. We encourage shortening the INTERVAL(EP-HSG), and the counseling of women on the most appropriate way to conceive thereafter.</description><identifier>ISSN: 0025-7974</identifier><identifier>EISSN: 1536-5964</identifier><identifier>DOI: 10.1097/MD.0000000000007263</identifier><identifier>PMID: 28640130</identifier><language>eng</language><publisher>United States: The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved</publisher><subject>Adult ; Age Factors ; Databases, Factual ; Female ; Humans ; Hysterosalpingography ; Infertility, Female - diagnostic imaging ; Infertility, Female - epidemiology ; Infertility, Female - prevention & control ; National Health Programs ; Observational Study ; Odds Ratio ; Postoperative Care ; Pregnancy ; Pregnancy, Ectopic - diagnostic imaging ; Pregnancy, Ectopic - epidemiology ; Pregnancy, Ectopic - surgery ; Retrospective Studies ; Taiwan ; Time Factors</subject><ispartof>Medicine (Baltimore), 2017-06, Vol.96 (25), p.e7263-e7263</ispartof><rights>The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved.</rights><rights>Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3559-60013a4cd0b599f04cc3730f3bda1d6db7b5514a0e8d8105c4d04de2e9046da63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484238/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484238/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28640130$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chiu, Nai-Chi</creatorcontrib><creatorcontrib>Ho, Chi-Hong</creatorcontrib><creatorcontrib>Shen, Shu-Huei</creatorcontrib><creatorcontrib>Tsuei, Yu-Chuan</creatorcontrib><creatorcontrib>Lee, Kang-Lung</creatorcontrib><creatorcontrib>Huang, Chen-Yu</creatorcontrib><creatorcontrib>Li, Hsin-Yang</creatorcontrib><creatorcontrib>Chen, Tzeng-Ji</creatorcontrib><title>Impact of hysterosalpingography after operative treatment for ectopic pregnancy in Taiwan: A 16-year Nationwide Population-Based Analysis</title><title>Medicine (Baltimore)</title><addtitle>Medicine (Baltimore)</addtitle><description>By retrieving records from Taiwan's National Health Insurance (NHI) system's database, the current study aimed to investigate the impacts of hysterosalpingography (HSG) to patients after ectopic pregnancy (EP) operations in Taiwan.In this retrospective cohort study, insurance claims data from 1997 to 2013, derived from a cohort of 1 million people randomly sampled to represent all NHI beneficiaries, were analyzed. Patients after ectopic pregnancy (EP) operations were identified via the inclusion of the corresponding NHI procedure codes. We further divided the patients into 2 groups by whether received subsequent HSG, EP-HSG, and EP-no-HSG. Patients with history of previous pregnancies (PP) and subsequent HSG were grouped as PP-HSG. We sought to evaluate the following pregnancies (FP) rate, interval to FP in EP-HSG compared with that in EP-no-HSG, and PP-HSG.EP-HSG had significantly higher FP rate odds ratio than EP-no-HSG (OR, 1.64; 95% CI, 1.24-2.16, P < .001). EP-HSG had lower FP rate odds ratio than that in PP-HSG, but no significant difference (33.1% vs 34.6%, P = .654). The INTERVAL(HSG-FP) in EP-HSG was no significantly different from that in PP-HSG (843.34 ± 82 days vs 644.72 ± 24.30 days, P = .077). There was significant positive correlation between FP after EP and number of HSG (r = 0.070, P < .001). There were significant negative correlation between FP and EP age (r = -0.270, P < .001), FP and INTERVAL(EP-HSG) (r = -0.212, P = .001). The multivariate analysis showed that INTERVAL(EP-HSG) less than 1 year is the predictor factor of INTERVAL(EP-FP) (hazard ratio: 1.422; 95% CI: 1.130-1.788; P = .003). It was evident that the longer the INTERVAL(EP-HSG), the lower the FP rate odds ratio; and the older the EP age, the lower the FP rate odds ratio. (OR, 95% CI; >1 year: 0.59, 0.41-0.86; >2 year: 0.42, 0.32-0.55; >25 years old: 0.47, 0.38-0.57; >30 years old: 0.29, 0.24-0.35; >35 years old: 0.12, 0.08-0.18, all P < .001).Receiving HSG after EP, short INTERVAL(EP-HSG), EP age less than 30 years old, had significant positive impacts on the FP. We encourage shortening the INTERVAL(EP-HSG), and the counseling of women on the most appropriate way to conceive thereafter.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Databases, Factual</subject><subject>Female</subject><subject>Humans</subject><subject>Hysterosalpingography</subject><subject>Infertility, Female - diagnostic imaging</subject><subject>Infertility, Female - epidemiology</subject><subject>Infertility, Female - prevention & control</subject><subject>National Health Programs</subject><subject>Observational Study</subject><subject>Odds Ratio</subject><subject>Postoperative Care</subject><subject>Pregnancy</subject><subject>Pregnancy, Ectopic - diagnostic imaging</subject><subject>Pregnancy, Ectopic - epidemiology</subject><subject>Pregnancy, Ectopic - surgery</subject><subject>Retrospective Studies</subject><subject>Taiwan</subject><subject>Time Factors</subject><issn>0025-7974</issn><issn>1536-5964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdUU1v1DAQtRCILoVfgIR85JJixx9JOCAtLR-VWuBQztbEnmwM2TjYSVf5Cf3XzXZLVfDFmuf33sz4EfKasxPOquLd5dkJe3SKXIsnZMWV0JmqtHxKVozlKiuqQh6RFyn9YoyLIpfPyVFearkUbEVuzrcD2JGGhrZzGjGGBN3g-03YRBjamUKzgDQMGGH010jHiDBusR9pEyJFO4bBWzpE3PTQ25n6nl6B30H_nq4p19mMEOm3RRv6nXdIf4Rh6u7K7CMkdHTdQzcnn16SZw10CV_d38fk5-dPV6dfs4vvX85P1xeZFUpVmd5vAdI6Vquqapi0VhSCNaJ2wJ12dVErxSUwLF3JmbLSMekwx4pJ7UCLY_Lh4DtM9RadXVaJ0Jkh-i3E2QTw5t-X3rdmE66NkqXMRbkYvL03iOHPhGk0W58sdh30GKZkeMVzzQul1UIVB6pd_jVFbB7acGb2IZrLM_N_iIvqzeMJHzR_U1sI8kDYhW5JJ_3uph1G0yJ0Y3vnp4oqz3LGC6ZzwbI9Uolb9lmqiQ</recordid><startdate>20170601</startdate><enddate>20170601</enddate><creator>Chiu, Nai-Chi</creator><creator>Ho, Chi-Hong</creator><creator>Shen, Shu-Huei</creator><creator>Tsuei, Yu-Chuan</creator><creator>Lee, Kang-Lung</creator><creator>Huang, Chen-Yu</creator><creator>Li, Hsin-Yang</creator><creator>Chen, Tzeng-Ji</creator><general>The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved</general><general>Wolters Kluwer Health</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20170601</creationdate><title>Impact of hysterosalpingography after operative treatment for ectopic pregnancy in Taiwan: A 16-year Nationwide Population-Based Analysis</title><author>Chiu, Nai-Chi ; Ho, Chi-Hong ; Shen, Shu-Huei ; Tsuei, Yu-Chuan ; Lee, Kang-Lung ; Huang, Chen-Yu ; Li, Hsin-Yang ; Chen, Tzeng-Ji</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3559-60013a4cd0b599f04cc3730f3bda1d6db7b5514a0e8d8105c4d04de2e9046da63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Databases, Factual</topic><topic>Female</topic><topic>Humans</topic><topic>Hysterosalpingography</topic><topic>Infertility, Female - diagnostic imaging</topic><topic>Infertility, Female - epidemiology</topic><topic>Infertility, Female - prevention & control</topic><topic>National Health Programs</topic><topic>Observational Study</topic><topic>Odds Ratio</topic><topic>Postoperative Care</topic><topic>Pregnancy</topic><topic>Pregnancy, Ectopic - diagnostic imaging</topic><topic>Pregnancy, Ectopic - epidemiology</topic><topic>Pregnancy, Ectopic - surgery</topic><topic>Retrospective Studies</topic><topic>Taiwan</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chiu, Nai-Chi</creatorcontrib><creatorcontrib>Ho, Chi-Hong</creatorcontrib><creatorcontrib>Shen, Shu-Huei</creatorcontrib><creatorcontrib>Tsuei, Yu-Chuan</creatorcontrib><creatorcontrib>Lee, Kang-Lung</creatorcontrib><creatorcontrib>Huang, Chen-Yu</creatorcontrib><creatorcontrib>Li, Hsin-Yang</creatorcontrib><creatorcontrib>Chen, Tzeng-Ji</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medicine (Baltimore)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chiu, Nai-Chi</au><au>Ho, Chi-Hong</au><au>Shen, Shu-Huei</au><au>Tsuei, Yu-Chuan</au><au>Lee, Kang-Lung</au><au>Huang, Chen-Yu</au><au>Li, Hsin-Yang</au><au>Chen, Tzeng-Ji</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impact of hysterosalpingography after operative treatment for ectopic pregnancy in Taiwan: A 16-year Nationwide Population-Based Analysis</atitle><jtitle>Medicine (Baltimore)</jtitle><addtitle>Medicine (Baltimore)</addtitle><date>2017-06-01</date><risdate>2017</risdate><volume>96</volume><issue>25</issue><spage>e7263</spage><epage>e7263</epage><pages>e7263-e7263</pages><issn>0025-7974</issn><eissn>1536-5964</eissn><abstract>By retrieving records from Taiwan's National Health Insurance (NHI) system's database, the current study aimed to investigate the impacts of hysterosalpingography (HSG) to patients after ectopic pregnancy (EP) operations in Taiwan.In this retrospective cohort study, insurance claims data from 1997 to 2013, derived from a cohort of 1 million people randomly sampled to represent all NHI beneficiaries, were analyzed. Patients after ectopic pregnancy (EP) operations were identified via the inclusion of the corresponding NHI procedure codes. We further divided the patients into 2 groups by whether received subsequent HSG, EP-HSG, and EP-no-HSG. Patients with history of previous pregnancies (PP) and subsequent HSG were grouped as PP-HSG. We sought to evaluate the following pregnancies (FP) rate, interval to FP in EP-HSG compared with that in EP-no-HSG, and PP-HSG.EP-HSG had significantly higher FP rate odds ratio than EP-no-HSG (OR, 1.64; 95% CI, 1.24-2.16, P < .001). EP-HSG had lower FP rate odds ratio than that in PP-HSG, but no significant difference (33.1% vs 34.6%, P = .654). The INTERVAL(HSG-FP) in EP-HSG was no significantly different from that in PP-HSG (843.34 ± 82 days vs 644.72 ± 24.30 days, P = .077). There was significant positive correlation between FP after EP and number of HSG (r = 0.070, P < .001). There were significant negative correlation between FP and EP age (r = -0.270, P < .001), FP and INTERVAL(EP-HSG) (r = -0.212, P = .001). The multivariate analysis showed that INTERVAL(EP-HSG) less than 1 year is the predictor factor of INTERVAL(EP-FP) (hazard ratio: 1.422; 95% CI: 1.130-1.788; P = .003). It was evident that the longer the INTERVAL(EP-HSG), the lower the FP rate odds ratio; and the older the EP age, the lower the FP rate odds ratio. (OR, 95% CI; >1 year: 0.59, 0.41-0.86; >2 year: 0.42, 0.32-0.55; >25 years old: 0.47, 0.38-0.57; >30 years old: 0.29, 0.24-0.35; >35 years old: 0.12, 0.08-0.18, all P < .001).Receiving HSG after EP, short INTERVAL(EP-HSG), EP age less than 30 years old, had significant positive impacts on the FP. We encourage shortening the INTERVAL(EP-HSG), and the counseling of women on the most appropriate way to conceive thereafter.</abstract><cop>United States</cop><pub>The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved</pub><pmid>28640130</pmid><doi>10.1097/MD.0000000000007263</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Age Factors Databases, Factual Female Humans Hysterosalpingography Infertility, Female - diagnostic imaging Infertility, Female - epidemiology Infertility, Female - prevention & control National Health Programs Observational Study Odds Ratio Postoperative Care Pregnancy Pregnancy, Ectopic - diagnostic imaging Pregnancy, Ectopic - epidemiology Pregnancy, Ectopic - surgery Retrospective Studies Taiwan Time Factors |
| title | Impact of hysterosalpingography after operative treatment for ectopic pregnancy in Taiwan: A 16-year Nationwide Population-Based Analysis |
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