Inhibition of N-methyl-N-nitrosourea-induced gastric tumorigenesis by Liuwei Dihuang Pill in db/db mice

AIM To investigate the inhibitory effect of Liuwei Dihuang Pill(LDP) on gastric tumorigenesis induced by N-methyl-N-nitrosourea(MNU) in diabetic mice.METHODS Four-week-old mice were divided into four groups: A, 12 db/m mice treated with MNU and saline, as the non-diabetic control; B, 12 db/db mice t...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2017-06, Vol.23 (23), p.4233-4242
Hauptverfasser:	Zhuang, Shan, Jian, Yong-Mei, Sun, Yong-Ning
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin - blood Animals Basic Study Blood Glucose - analysis Body Weight Carcinogenesis Cell Transformation, Neoplastic Diabetes Mellitus, Experimental Drugs, Chinese Herbal - pharmacology Immunohistochemistry Insulin - blood Insulin Resistance Insulin-Like Growth Factor I - metabolism Ki-67 Antigen - blood Leptin - blood Male Methylnitrosourea Mice Stomach Neoplasms - chemically induced Stomach Neoplasms - drug therapy
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